Abstract
We have formulated a gradient model of the rabbit sinoatrial node based on cell-specific ionic models of electrical activity from its central and peripheral regions. The gradient model exhibits a smooth transition in action potential characteristics such as maximum diastolic potential, overshoot potential, upstroke velocity, action potential duration and cycle length, and is suitable for developing higher dimensional models of the right atrium. Spontaneous pacemaker activity is simulated in a one-dimensional monodomain model of the sinoatrial node and adjoining atrial tissue.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2003 |
| Pages | 24-27 |
| Number of pages | 4 |
| Volume | 25 |
| Publication status | Published - 2003 |
| Externally published | Yes |
| Event | International Conference of the IEEE Engineering in Medicine and Biology Society 2003 - Cancun, Mexico Duration: 17 Sept 2003 → 21 Sept 2003 Conference number: 25th https://ieeexplore.ieee.org/xpl/conhome/9009/proceeding?isnumber=28608 (Proceedings) |
Conference
| Conference | International Conference of the IEEE Engineering in Medicine and Biology Society 2003 |
|---|---|
| Abbreviated title | EMBC 2003 |
| Country/Territory | Mexico |
| City | Cancun |
| Period | 17/09/03 → 21/09/03 |
| Internet address |