A gradient model of the rabbit sinoatrial node

SL Cloherty, S Dokos, NH Lovell

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Abstract

We have formulated a gradient model of the rabbit sinoatrial node based on cell-specific ionic models of electrical activity from its central and peripheral regions. The gradient model exhibits a smooth transition in action potential characteristics such as maximum diastolic potential, overshoot potential, upstroke velocity, action potential duration and cycle length, and is suitable for developing higher dimensional models of the right atrium. Spontaneous pacemaker activity is simulated in a one-dimensional monodomain model of the sinoatrial node and adjoining atrial tissue.
Original languageEnglish
Title of host publicationProceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vols 1-4: A New Beginning for Human Health
Pages24-27
Number of pages4
Volume25
Publication statusPublished - 2003
Externally publishedYes
EventInternational Conference of the IEEE Engineering in Medicine and Biology Society 2003 - Cancun, Mexico
Duration: 17 Sep 200321 Sep 2003
Conference number: 25th
https://ieeexplore.ieee.org/xpl/conhome/9009/proceeding?isnumber=28608 (Proceedings)

Conference

ConferenceInternational Conference of the IEEE Engineering in Medicine and Biology Society 2003
Abbreviated titleEMBC 2003
CountryMexico
CityCancun
Period17/09/0321/09/03
Internet address

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