A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry

Amandeep Kaur, Mohammad A. Haghighatbin, Conor F. Hogan, Elizabeth J. New

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Abstract

Understanding the role of oxidative stress in disease requires real time monitoring of redox status within a cell. We report a FRET-based, ratiometric redox probe which can be applied to monitor cellular oxidative capacity using three different modalities - confocal microscopy, fluorescence lifetime imaging and flow cytometry.

Original languageEnglish
Pages (from-to)10510-10513
Number of pages4
JournalChemical Communications
Volume51
Issue number52
DOIs
Publication statusPublished - 4 Jul 2015
Externally publishedYes

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