A frequently missed entity in systemic lupus erythematosus (SLE): Intestinal pseudo-obstruction (IpsO)

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Intestinal pseudo-obstruction (IpsO) is defined as presence of clinical features of intestinal obstruction without identifiable mechanical obstructive lesion. IpsO is an uncommon gastrointestinal manifestation of systemic lupus erythematosus (SLE) and is largely under-recognised. There are only over 30 published cases in English literature on SLE-related IpsO. Herein, we report two cases of SLE-related IpsO to illustrate the importance of early recognition to avoid unnecessary surgical intervention, as SLE-related IpsO responds well to systemic high dose corticosteroids. These two cases also demonstrate the apparent association of IpsO with uretero-hydronephrosis, suggesting that the possible mechanism could be smooth muscle dysmotility.

Original languageEnglish
Pages (from-to)374-375
Number of pages2
JournalMedical Journal of Malaysia
Issue number6
Publication statusPublished - Dec 2017
Externally publishedYes


  • Autoimmune
  • Intestinal pseudo-obstruction
  • Smooth muscle dysmotility
  • Systemic corticosteroid
  • Systemic lupus erythematosus
  • Uretero-hydronephrosis

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