A first dataset toward a standardized community-driven global mapping of the human immunopeptidome

Pouya Faridi, Ruedi Aebersold, Etienne Caron

Research output: Contribution to journalArticleOtherpeer-review

8 Citations (Scopus)

Abstract

We present the first standardized HLA peptidomics dataset generated by the immunopeptidomics community. The dataset is composed of native HLA class I peptides as well as synthetic HLA class II peptides that were acquired in data-dependent acquisition mode using multiple types of mass spectrometers. All laboratories used the spiked-in landmark iRT peptides for retention time normalization and data analysis. The mass spectrometric data were deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD001872. The generated data were used to build HLA allele-specific peptide spectral and assay libraries, which were stored in the SWATHAtlas database. Data presented here are described in more detail in the original eLife article entitled 'An open-source computational and data resource to analyze digital maps of immunopeptidomes'.

Original languageEnglish
Pages (from-to)201-205
Number of pages5
JournalData in Brief
Volume7
DOIs
Publication statusPublished - 1 Jun 2016
Externally publishedYes

Keywords

  • HLA
  • Immunology
  • Mass spectrometry
  • Peptidomics

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