TY - JOUR
T1 - A double‐blind crossover comparison of pindolol, metoprolol, atenolol and labetalol in mild to moderate hypertension.
AU - McNeil, JJ
AU - Louis, WJ
PY - 1979/1/1
Y1 - 1979/1/1
N2 - 1 This study was designed to compare in a double‐blind randomized crossover trial, atenolol, labetalol, metoprolol and pindolol. Considerable differences in dose (atenolol 138 +/‐ 13 mg daily; labetalol 308 +/‐ 34 mg daily; metoprolol 234 +/‐ 22 mg daily; and pindolol 24 +/‐2 mg daily were required to produce similar antihypertensive effects. 3 The overall incidence of side‐effects was similar with atenolol, metoprolol and pindolol but was slightly less with labetalol. Sleep disturbances and abnormal dreaming patterns were most frequent with pindolol. 4 There was a significantly greater fall in pulse rate during atenolol and metoprolol treatment periods. 1979 The British Pharmacological Society
AB - 1 This study was designed to compare in a double‐blind randomized crossover trial, atenolol, labetalol, metoprolol and pindolol. Considerable differences in dose (atenolol 138 +/‐ 13 mg daily; labetalol 308 +/‐ 34 mg daily; metoprolol 234 +/‐ 22 mg daily; and pindolol 24 +/‐2 mg daily were required to produce similar antihypertensive effects. 3 The overall incidence of side‐effects was similar with atenolol, metoprolol and pindolol but was slightly less with labetalol. Sleep disturbances and abnormal dreaming patterns were most frequent with pindolol. 4 There was a significantly greater fall in pulse rate during atenolol and metoprolol treatment periods. 1979 The British Pharmacological Society
UR - https://www.scopus.com/pages/publications/0018631708
U2 - 10.1111/j.1365-2125.1979.tb04774.x
DO - 10.1111/j.1365-2125.1979.tb04774.x
M3 - Article
C2 - 43164
AN - SCOPUS:0018631708
SN - 0306-5251
VL - 8
SP - 163S-166S
JO - British Journal of Clinical Pharmacology
JF - British Journal of Clinical Pharmacology
IS - 2 S
ER -