A diverse suite of pharmaceuticals contaminates stream and riparian food webs

Erinn K. Richmond, Emma J. Rosi, David M. Walters, Jerker Fick, Stephen K. Hamilton, Tomas Brodin, Anna Sundelin, Michael R. Grace

Research output: Contribution to journalArticleResearchpeer-review

Abstract

A multitude of biologically active pharmaceuticals contaminate surface waters globally, yet their presence in aquatic food webs remain largely unknown. Here, we show that over 60 pharmaceutical compounds can be detected in aquatic invertebrates and riparian spiders in six streams near Melbourne, Australia. Similar concentrations in aquatic invertebrate larvae and riparian predators suggest direct trophic transfer via emerging adult insects to riparian predators that consume them. As representative vertebrate predators feeding on aquatic invertebrates, platypus and brown trout could consume some drug classes such as antidepressants at as much as one-half of a recommended therapeutic dose for humans based on their estimated prey consumption rates, yet the consequences for fish and wildlife of this chronic exposure are unknown. Overall, this work highlights the potential exposure of aquatic and riparian biota to a diverse array of pharmaceuticals, resulting in exposures to some drugs that are comparable to human dosages.

Original languageEnglish
Article number4491
Number of pages9
JournalNature Communications
Volume9
Issue number1
DOIs
Publication statusPublished - 1 Dec 2018

Keywords

  • Pharmaceuticals
  • Stream Ecology
  • Invertebrates
  • Riparian spiders
  • Emergence
  • LS-MS-MS

Cite this

Richmond, Erinn K. ; Rosi, Emma J. ; Walters, David M. ; Fick, Jerker ; Hamilton, Stephen K. ; Brodin, Tomas ; Sundelin, Anna ; Grace, Michael R. / A diverse suite of pharmaceuticals contaminates stream and riparian food webs. In: Nature Communications. 2018 ; Vol. 9, No. 1.
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abstract = "A multitude of biologically active pharmaceuticals contaminate surface waters globally, yet their presence in aquatic food webs remain largely unknown. Here, we show that over 60 pharmaceutical compounds can be detected in aquatic invertebrates and riparian spiders in six streams near Melbourne, Australia. Similar concentrations in aquatic invertebrate larvae and riparian predators suggest direct trophic transfer via emerging adult insects to riparian predators that consume them. As representative vertebrate predators feeding on aquatic invertebrates, platypus and brown trout could consume some drug classes such as antidepressants at as much as one-half of a recommended therapeutic dose for humans based on their estimated prey consumption rates, yet the consequences for fish and wildlife of this chronic exposure are unknown. Overall, this work highlights the potential exposure of aquatic and riparian biota to a diverse array of pharmaceuticals, resulting in exposures to some drugs that are comparable to human dosages.",
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A diverse suite of pharmaceuticals contaminates stream and riparian food webs. / Richmond, Erinn K.; Rosi, Emma J.; Walters, David M.; Fick, Jerker; Hamilton, Stephen K.; Brodin, Tomas; Sundelin, Anna; Grace, Michael R.

In: Nature Communications, Vol. 9, No. 1, 4491, 01.12.2018.

Research output: Contribution to journalArticleResearchpeer-review

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