A direct method for the formation of peptide and carbohydrate dendrimers

Jeffrey P. Mitchell, Kade D. Roberts, Jane Langley, Frank Koentgen, John N. Lambert

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)

Abstract

Two new methods for the modification of PAMAM dendrimers have been developed which allow the covergent synthesis of either peptide or carbohydrate-bearing dendrimer molecules. Both methods involve condensation between hydroxylamino nucleophiles and appropriate carbonyl-bearing reaction partners.

Original languageEnglish
Pages (from-to)2785-2788
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume9
Issue number19
DOIs
Publication statusPublished - 4 Oct 1999
Externally publishedYes

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