A Decade of the Protein Corona

Pu Chun Ke, Sijie Lin, Wolfgang J. Parak, Thomas P. Davis, Frank Caruso

Research output: Contribution to journalReview ArticleResearchpeer-review

88 Citations (Scopus)

Abstract

In this Perspective, we reflect on a decade of research on the protein corona and contemplate its broad implications for future science and engineering at the bio-nano interface. Specifically, we focus on the physical origins and time evolution of the protein corona, differences in the nanoparticle-protein entity in in vitro and in vivo environments, the role of stealth polymers to minimize the formation of the protein corona, relevant computational and theoretical developments, and the "biocorona", a concept extrapolated from the field of nanomedicine. We conclude the Perspective by outlining future directions and opportunities concerning the protein corona in the coming decade.

Original languageEnglish
Pages (from-to)11773-11776
Number of pages4
JournalACS Nano
Volume11
Issue number12
DOIs
Publication statusPublished - 26 Dec 2017

Cite this

Ke, P. C., Lin, S., Parak, W. J., Davis, T. P., & Caruso, F. (2017). A Decade of the Protein Corona. ACS Nano, 11(12), 11773-11776. https://doi.org/10.1021/acsnano.7b08008
Ke, Pu Chun ; Lin, Sijie ; Parak, Wolfgang J. ; Davis, Thomas P. ; Caruso, Frank. / A Decade of the Protein Corona. In: ACS Nano. 2017 ; Vol. 11, No. 12. pp. 11773-11776.
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Ke, PC, Lin, S, Parak, WJ, Davis, TP & Caruso, F 2017, 'A Decade of the Protein Corona', ACS Nano, vol. 11, no. 12, pp. 11773-11776. https://doi.org/10.1021/acsnano.7b08008

A Decade of the Protein Corona. / Ke, Pu Chun; Lin, Sijie; Parak, Wolfgang J.; Davis, Thomas P.; Caruso, Frank.

In: ACS Nano, Vol. 11, No. 12, 26.12.2017, p. 11773-11776.

Research output: Contribution to journalReview ArticleResearchpeer-review

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Ke PC, Lin S, Parak WJ, Davis TP, Caruso F. A Decade of the Protein Corona. ACS Nano. 2017 Dec 26;11(12):11773-11776. https://doi.org/10.1021/acsnano.7b08008