A coupled CFD-resistive network analogy model to investigate the intraocular pressure in glaucomatous eyes

Ooi Ean Hin; Harjindar Singh Chahl; Norlina Ramli; Amir Samsudin

A coupled CFD-resistive network analogy model to investigate the intraocular pressure in glaucomatous eyes

Ooi Ean Hin, Harjindar Singh Chahl, Norlina Ramli, Amir Samsudin

Malaysia School of Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

Abstract

A resistive network analogy (RNA) model that provides a platform for linking the computational fluid dynamics study of aqueous humor (AH) flow to the anatomical/physiological changes associated with glaucoma is proposed. The RNA model is based on an electrical resistor circuit analogy and is formulated around the hydrodynamic funneling model. Results show that the pore density of normal and glaucomatous eyes produced intraocular pressure (IOP) that correspond to healthy and pathologic conditions. IOP also increases exponentially with decreasing pore density, suggesting that the degree of optic nerve damage in glaucoma may increase rapidly during the latter stages of development.

Original language	English
Title of host publication	Proceedings of the 4th International Conference on Computational & Mathematical Biomedical Engineering (CMBE15)
Editors	Perumal Nithiarasu, Elisa Budyn
Place of Publication	Swansea UK
Publisher	CMBE
Pages	620 - 623
Number of pages	4
Publication status	Published - 2015
Event	International Conference on Computational and Mathematical Biomedical Engineering 2015 - Ecole Normale Superieure de Cachan, Cachen, France Duration: 29 Jun 2015 → 1 Jul 2015 Conference number: 4th http://www.compbiomed.net/2015/

Conference

Conference	International Conference on Computational and Mathematical Biomedical Engineering 2015
Abbreviated title	CMBE 2015
Country/Territory	France
City	Cachen
Period	29/06/15 → 1/07/15
Internet address	http://www.compbiomed.net/2015/

Cite this

@inproceedings{ab2d54ad9e404163a13718597e718860,

title = "A coupled CFD-resistive network analogy model to investigate the intraocular pressure in glaucomatous eyes",

abstract = "A resistive network analogy (RNA) model that provides a platform for linking the computational fluid dynamics study of aqueous humor (AH) flow to the anatomical/physiological changes associated with glaucoma is proposed. The RNA model is based on an electrical resistor circuit analogy and is formulated around the hydrodynamic funneling model. Results show that the pore density of normal and glaucomatous eyes produced intraocular pressure (IOP) that correspond to healthy and pathologic conditions. IOP also increases exponentially with decreasing pore density, suggesting that the degree of optic nerve damage in glaucoma may increase rapidly during the latter stages of development.",

author = "Hin, \{Ooi Ean\} and Chahl, \{Harjindar Singh\} and Norlina Ramli and Amir Samsudin",

year = "2015",

language = "English",

pages = "620 -- 623",

editor = "Perumal Nithiarasu and Elisa Budyn",

booktitle = "Proceedings of the 4th International Conference on Computational \& Mathematical Biomedical Engineering (CMBE15)",

publisher = "CMBE",

note = "International Conference on Computational and Mathematical Biomedical Engineering 2015, CMBE 2015 ; Conference date: 29-06-2015 Through 01-07-2015",

url = "http://www.compbiomed.net/2015/",

}

Hin, OE, Chahl, HS, Ramli, N & Samsudin, A 2015, A coupled CFD-resistive network analogy model to investigate the intraocular pressure in glaucomatous eyes. in P Nithiarasu & E Budyn (eds), Proceedings of the 4th International Conference on Computational & Mathematical Biomedical Engineering (CMBE15). CMBE, Swansea UK, pp. 620 - 623, International Conference on Computational and Mathematical Biomedical Engineering 2015, Cachen, France, 29/06/15.

A coupled CFD-resistive network analogy model to investigate the intraocular pressure in glaucomatous eyes. / Hin, Ooi Ean; Chahl, Harjindar Singh; Ramli, Norlina et al.
Proceedings of the 4th International Conference on Computational & Mathematical Biomedical Engineering (CMBE15). ed. / Perumal Nithiarasu; Elisa Budyn. Swansea UK: CMBE, 2015. p. 620 - 623.

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

TY - GEN

T1 - A coupled CFD-resistive network analogy model to investigate the intraocular pressure in glaucomatous eyes

AU - Hin, Ooi Ean

AU - Chahl, Harjindar Singh

AU - Ramli, Norlina

AU - Samsudin, Amir

N1 - Conference code: 4th

PY - 2015

Y1 - 2015

N2 - A resistive network analogy (RNA) model that provides a platform for linking the computational fluid dynamics study of aqueous humor (AH) flow to the anatomical/physiological changes associated with glaucoma is proposed. The RNA model is based on an electrical resistor circuit analogy and is formulated around the hydrodynamic funneling model. Results show that the pore density of normal and glaucomatous eyes produced intraocular pressure (IOP) that correspond to healthy and pathologic conditions. IOP also increases exponentially with decreasing pore density, suggesting that the degree of optic nerve damage in glaucoma may increase rapidly during the latter stages of development.

AB - A resistive network analogy (RNA) model that provides a platform for linking the computational fluid dynamics study of aqueous humor (AH) flow to the anatomical/physiological changes associated with glaucoma is proposed. The RNA model is based on an electrical resistor circuit analogy and is formulated around the hydrodynamic funneling model. Results show that the pore density of normal and glaucomatous eyes produced intraocular pressure (IOP) that correspond to healthy and pathologic conditions. IOP also increases exponentially with decreasing pore density, suggesting that the degree of optic nerve damage in glaucoma may increase rapidly during the latter stages of development.

M3 - Conference Paper

SP - 620

EP - 623

BT - Proceedings of the 4th International Conference on Computational & Mathematical Biomedical Engineering (CMBE15)

A2 - Nithiarasu, Perumal

A2 - Budyn, Elisa

PB - CMBE

CY - Swansea UK

T2 - International Conference on Computational and Mathematical Biomedical Engineering 2015

Y2 - 29 June 2015 through 1 July 2015

ER -