TY - JOUR
T1 - A comparison of MEmory Specificity Training (MEST) to education and support (ES) in the treatment of recurrent depression: study protocol for a cluster randomised controlled trial
AU - Dalgleish, Tim
AU - Bevan, Anna
AU - McKinnon, Anna
AU - Breakwell, Lauren
AU - Mueller, Viola
AU - Chadwick, Isobel
AU - Schweizer, Susanne
AU - Hitchcock, Caitlin
AU - Watson, Peter C
AU - Raes, Filip
AU - Jobson, Laura
AU - Werner-Seidler, Aliza
PY - 2014
Y1 - 2014
N2 - Background: Depression is a debilitating mental health problem that tends to run a chronic, recurrent course. Even when effectively treated, relapse and recurrence rates remain high. Accordingly, interventions need to focus not only on symptom reduction, but also on reducing the risk of relapse by targeting depression-related disturbances that persist into remission. We are addressing this need by investigating the efficacy, acceptability and feasibility of a MEmory Specificity Training (MEST) programme, which directly targets an enduring cognitive marker of depression - reduced autobiographical memory specificity. Promising pilot data suggest that training memory specificity ameliorates this disturbance and reduces depressive symptoms. A larger, controlled trial is now needed to examine the efficacy of MEST. This trial compares MEST to an education and support (ES) group, with an embedded mechanism study.
AB - Background: Depression is a debilitating mental health problem that tends to run a chronic, recurrent course. Even when effectively treated, relapse and recurrence rates remain high. Accordingly, interventions need to focus not only on symptom reduction, but also on reducing the risk of relapse by targeting depression-related disturbances that persist into remission. We are addressing this need by investigating the efficacy, acceptability and feasibility of a MEmory Specificity Training (MEST) programme, which directly targets an enduring cognitive marker of depression - reduced autobiographical memory specificity. Promising pilot data suggest that training memory specificity ameliorates this disturbance and reduces depressive symptoms. A larger, controlled trial is now needed to examine the efficacy of MEST. This trial compares MEST to an education and support (ES) group, with an embedded mechanism study.
UR - http://www.trialsjournal.com/content/pdf/1745-6215-15-293.pdf
U2 - 10.1186/1745-6215-15-293
DO - 10.1186/1745-6215-15-293
M3 - Article
VL - 15
JO - Trials
JF - Trials
SN - 1745-6215
M1 - 293
ER -
