A comparison of effectiveness between oral rapid testing and routine serum-based testing for HIV in an outpatient dental clinic in Yuxi Prefecture, China

A case-control study

Shifu Li, Shu Su, Shunxiang Li, Liangmin Gao, Ying Cai, Jincui Fu, Chunyuan Guo, Wei Lu, Feng Cheng, Jun Jing, Liang Chen, Lei Zhang

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objective To compare the outcomes of routine provider-initiated HIV testing and counselling (PITC) and oral rapid HIV testing for dental clinic outpatients in a hospital. Design We employed a case-control study design and recruited dental outpatients into routine serum-based and oral rapid testing groups. We compared the acceptance, completion and result notification rate between groups. Setting A dental outpatient clinic in the Yuxi People's Hospital, Yunnan. Participants A total of 758 and 816 dental outpatients were enrolled for routine and oral rapid testing, respectively. Results The percentage of participants willing to receive routine HIV testing was 28.1% (95% CI 24.9% to 31.3%) and 96.1% (95% CI 94.8% to 97.4%, Ï ‡2=186.4, p<0.001) for the rapid testing. Among accepted participants, the percentage of participants who received HIV testing was 26.8% (95% CI 20.9% to 32.7%) in the routine testing group and 100.0% in the oral rapid HIV testing group (Ï ‡2=77.5, p<0.001). About 93.0% of routine testers returned for the test results on the next day, whereas all rapid testers received their test results on the same day (Ï ‡2=34.6, p<0.001). These correspond to an overall completion rate of 7.0% (95% CI 5.2% to 8.8%) and 96.1% (95% CI 94.8% to 97.4%, p<0.001), respectively. Among the 545 patients who declined routine serum-based HIV testing, the main reasons included, an unnecessary hassle (254/545, 46.6%), having been previously tested (124/545, 22.8%) and self-perceived low risk of HIV infection (103/545, 18.9%). In contrast, only 32 individuals declined oral rapid testing, and having received a previous test was the primary reason. Three patients in the rapid testing group were later confirmed HIV-positive, yielding an HIV prevalence of 0.38%. Conclusion Oral rapid HIV testing is a feasible and efficient approach in a clinical setting.

Original languageEnglish
Article numbere014601
Number of pages8
JournalBMJ Open
Volume7
Issue number6
DOIs
Publication statusPublished - 1 Jun 2017

Keywords

  • Dental clinic outpatients
  • HIV
  • Improve
  • Oral rapid test
  • PITC

Cite this

Li, Shifu ; Su, Shu ; Li, Shunxiang ; Gao, Liangmin ; Cai, Ying ; Fu, Jincui ; Guo, Chunyuan ; Lu, Wei ; Cheng, Feng ; Jing, Jun ; Chen, Liang ; Zhang, Lei. / A comparison of effectiveness between oral rapid testing and routine serum-based testing for HIV in an outpatient dental clinic in Yuxi Prefecture, China : A case-control study. In: BMJ Open. 2017 ; Vol. 7, No. 6.
@article{9447eacb18c6430581a719a5ceefbd48,
title = "A comparison of effectiveness between oral rapid testing and routine serum-based testing for HIV in an outpatient dental clinic in Yuxi Prefecture, China: A case-control study",
abstract = "Objective To compare the outcomes of routine provider-initiated HIV testing and counselling (PITC) and oral rapid HIV testing for dental clinic outpatients in a hospital. Design We employed a case-control study design and recruited dental outpatients into routine serum-based and oral rapid testing groups. We compared the acceptance, completion and result notification rate between groups. Setting A dental outpatient clinic in the Yuxi People's Hospital, Yunnan. Participants A total of 758 and 816 dental outpatients were enrolled for routine and oral rapid testing, respectively. Results The percentage of participants willing to receive routine HIV testing was 28.1{\%} (95{\%} CI 24.9{\%} to 31.3{\%}) and 96.1{\%} (95{\%} CI 94.8{\%} to 97.4{\%}, {\"I} ‡2=186.4, p<0.001) for the rapid testing. Among accepted participants, the percentage of participants who received HIV testing was 26.8{\%} (95{\%} CI 20.9{\%} to 32.7{\%}) in the routine testing group and 100.0{\%} in the oral rapid HIV testing group ({\"I} ‡2=77.5, p<0.001). About 93.0{\%} of routine testers returned for the test results on the next day, whereas all rapid testers received their test results on the same day ({\"I} ‡2=34.6, p<0.001). These correspond to an overall completion rate of 7.0{\%} (95{\%} CI 5.2{\%} to 8.8{\%}) and 96.1{\%} (95{\%} CI 94.8{\%} to 97.4{\%}, p<0.001), respectively. Among the 545 patients who declined routine serum-based HIV testing, the main reasons included, an unnecessary hassle (254/545, 46.6{\%}), having been previously tested (124/545, 22.8{\%}) and self-perceived low risk of HIV infection (103/545, 18.9{\%}). In contrast, only 32 individuals declined oral rapid testing, and having received a previous test was the primary reason. Three patients in the rapid testing group were later confirmed HIV-positive, yielding an HIV prevalence of 0.38{\%}. Conclusion Oral rapid HIV testing is a feasible and efficient approach in a clinical setting.",
keywords = "Dental clinic outpatients, HIV, Improve, Oral rapid test, PITC",
author = "Shifu Li and Shu Su and Shunxiang Li and Liangmin Gao and Ying Cai and Jincui Fu and Chunyuan Guo and Wei Lu and Feng Cheng and Jun Jing and Liang Chen and Lei Zhang",
year = "2017",
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doi = "10.1136/bmjopen-2016-014601",
language = "English",
volume = "7",
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A comparison of effectiveness between oral rapid testing and routine serum-based testing for HIV in an outpatient dental clinic in Yuxi Prefecture, China : A case-control study. / Li, Shifu; Su, Shu; Li, Shunxiang; Gao, Liangmin; Cai, Ying; Fu, Jincui; Guo, Chunyuan; Lu, Wei; Cheng, Feng; Jing, Jun; Chen, Liang; Zhang, Lei.

In: BMJ Open, Vol. 7, No. 6, e014601, 01.06.2017.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - A comparison of effectiveness between oral rapid testing and routine serum-based testing for HIV in an outpatient dental clinic in Yuxi Prefecture, China

T2 - A case-control study

AU - Li, Shifu

AU - Su, Shu

AU - Li, Shunxiang

AU - Gao, Liangmin

AU - Cai, Ying

AU - Fu, Jincui

AU - Guo, Chunyuan

AU - Lu, Wei

AU - Cheng, Feng

AU - Jing, Jun

AU - Chen, Liang

AU - Zhang, Lei

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Objective To compare the outcomes of routine provider-initiated HIV testing and counselling (PITC) and oral rapid HIV testing for dental clinic outpatients in a hospital. Design We employed a case-control study design and recruited dental outpatients into routine serum-based and oral rapid testing groups. We compared the acceptance, completion and result notification rate between groups. Setting A dental outpatient clinic in the Yuxi People's Hospital, Yunnan. Participants A total of 758 and 816 dental outpatients were enrolled for routine and oral rapid testing, respectively. Results The percentage of participants willing to receive routine HIV testing was 28.1% (95% CI 24.9% to 31.3%) and 96.1% (95% CI 94.8% to 97.4%, Ï ‡2=186.4, p<0.001) for the rapid testing. Among accepted participants, the percentage of participants who received HIV testing was 26.8% (95% CI 20.9% to 32.7%) in the routine testing group and 100.0% in the oral rapid HIV testing group (Ï ‡2=77.5, p<0.001). About 93.0% of routine testers returned for the test results on the next day, whereas all rapid testers received their test results on the same day (Ï ‡2=34.6, p<0.001). These correspond to an overall completion rate of 7.0% (95% CI 5.2% to 8.8%) and 96.1% (95% CI 94.8% to 97.4%, p<0.001), respectively. Among the 545 patients who declined routine serum-based HIV testing, the main reasons included, an unnecessary hassle (254/545, 46.6%), having been previously tested (124/545, 22.8%) and self-perceived low risk of HIV infection (103/545, 18.9%). In contrast, only 32 individuals declined oral rapid testing, and having received a previous test was the primary reason. Three patients in the rapid testing group were later confirmed HIV-positive, yielding an HIV prevalence of 0.38%. Conclusion Oral rapid HIV testing is a feasible and efficient approach in a clinical setting.

AB - Objective To compare the outcomes of routine provider-initiated HIV testing and counselling (PITC) and oral rapid HIV testing for dental clinic outpatients in a hospital. Design We employed a case-control study design and recruited dental outpatients into routine serum-based and oral rapid testing groups. We compared the acceptance, completion and result notification rate between groups. Setting A dental outpatient clinic in the Yuxi People's Hospital, Yunnan. Participants A total of 758 and 816 dental outpatients were enrolled for routine and oral rapid testing, respectively. Results The percentage of participants willing to receive routine HIV testing was 28.1% (95% CI 24.9% to 31.3%) and 96.1% (95% CI 94.8% to 97.4%, Ï ‡2=186.4, p<0.001) for the rapid testing. Among accepted participants, the percentage of participants who received HIV testing was 26.8% (95% CI 20.9% to 32.7%) in the routine testing group and 100.0% in the oral rapid HIV testing group (Ï ‡2=77.5, p<0.001). About 93.0% of routine testers returned for the test results on the next day, whereas all rapid testers received their test results on the same day (Ï ‡2=34.6, p<0.001). These correspond to an overall completion rate of 7.0% (95% CI 5.2% to 8.8%) and 96.1% (95% CI 94.8% to 97.4%, p<0.001), respectively. Among the 545 patients who declined routine serum-based HIV testing, the main reasons included, an unnecessary hassle (254/545, 46.6%), having been previously tested (124/545, 22.8%) and self-perceived low risk of HIV infection (103/545, 18.9%). In contrast, only 32 individuals declined oral rapid testing, and having received a previous test was the primary reason. Three patients in the rapid testing group were later confirmed HIV-positive, yielding an HIV prevalence of 0.38%. Conclusion Oral rapid HIV testing is a feasible and efficient approach in a clinical setting.

KW - Dental clinic outpatients

KW - HIV

KW - Improve

KW - Oral rapid test

KW - PITC

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U2 - 10.1136/bmjopen-2016-014601

DO - 10.1136/bmjopen-2016-014601

M3 - Article

VL - 7

JO - BMJ Open

JF - BMJ Open

SN - 2044-6055

IS - 6

M1 - e014601

ER -