A comparative study on liquid core formulation on the diameter on the alginate capsules

Hui-Yen Ong, Boon-Beng Lee, Akmal Hadi Ma Radzi, Zarina Zakaria, Eng Seng Chan

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    1 Citation (Scopus)

    Abstract

    Liquid core capsule has vast application in biotechnology related industries such as pharmaceutical, medical, agriculture and food. Formulation of different types of capsule was important to determine the performance of the capsule. Generally, the liquid core capsule with different formulations generated different size of capsule.Therefore, the aim of this project is to investigate the effect of different liquid core solution formulations on the diameter of capsule. The capsule produced by extruding liquid core solutions into sodium alginate solution. Three types of liquid core solutions (chitosan, xanthan gum, polyethylene glycol (PEG)) were investigated. The results showed that there is significant change in capsule diameter despite in different types of liquid core solution were used and a series of capsule range in diameter of 3.1 mm to 4.5 mm were produced. Alginate capsule with chitosan formulation appeared to be the largest capsule among all.
    Original languageEnglish
    Title of host publicationProceedings of the Physics and Materials Symposium: International Conference on Applied Science and Industrial Technology (ICASIT2015)
    EditorsTan Winie, R H Y Subban, F H Muhammad
    Place of PublicationNew York USA
    PublisherAIP Publishing
    Pages1 - 6
    Number of pages6
    Volume1674
    ISBN (Print)9780735413214
    DOIs
    Publication statusPublished - 2015
    EventPhysics and Materials Symposium: International Conference on Applied Science and Industrial Technology (ICASIT2015) - Negeri Sembilan Malaysia, New York USA
    Duration: 1 Jan 2015 → …

    Conference

    ConferencePhysics and Materials Symposium: International Conference on Applied Science and Industrial Technology (ICASIT2015)
    CityNew York USA
    Period1/01/15 → …

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