Hydrocephalus refers to an abnormal accumulation of cerebral spinal fluid (CSF) within the brain resulting in enlarged ventricles and subsequent distortion of periventricular structures , while normal pressure hydrocephalus (NPH) is a specific form of communicating hydrocephalus where intra-ventricular CSF pressure remains in the normal range. As only a small disparity in pressure between the ventricles and surrounding subarachnoid space are needed to trigger absorption of interstitial fluid, ventricular enlargement still occurs in this condition , which is typically accompanied by symptoms of gait disturbance, urinary incontinence and cognitive impairment . Although a number of movement disorders have been described in patients with hydrocephalus , the occurrence of tremor is a rare finding, which has consequently received very little attention in the literature and warrants further investigation. Here we present a case of an appendicular, predominantly lower-limb tremor occurring in a patient with concomitant idiopathic NPH, which demonstrated a marked reduction in amplitude following the insertion of a ventriculo-peritoneal shunt. The potential mechanisms underlying this clinical presentation are also discussed.
Hill, A., Cowey, M., & Williams, D. (2014). A case of shunt responsive tremor due to normal pressure hydrocephalus. Journal of the Neurological Sciences, 347, 413 - 415. https://doi.org/10.1016/j.jns.2014.11.002