A case of shunt responsive tremor due to normal pressure hydrocephalus

Aron Hill, Max Cowey, David Williams

Research output: Contribution to journalLetterOther


Hydrocephalus refers to an abnormal accumulation of cerebral spinal fluid (CSF) within the brain resulting in enlarged ventricles and subsequent distortion of periventricular structures [1], while normal pressure hydrocephalus (NPH) is a specific form of communicating hydrocephalus where intra-ventricular CSF pressure remains in the normal range. As only a small disparity in pressure between the ventricles and surrounding subarachnoid space are needed to trigger absorption of interstitial fluid, ventricular enlargement still occurs in this condition [2], which is typically accompanied by symptoms of gait disturbance, urinary incontinence and cognitive impairment [3]. Although a number of movement disorders have been described in patients with hydrocephalus [4], the occurrence of tremor is a rare finding, which has consequently received very little attention in the literature and warrants further investigation. Here we present a case of an appendicular, predominantly lower-limb tremor occurring in a patient with concomitant idiopathic NPH, which demonstrated a marked reduction in amplitude following the insertion of a ventriculo-peritoneal shunt. The potential mechanisms underlying this clinical presentation are also discussed.
Original languageEnglish
Pages (from-to)413 - 415
Number of pages3
JournalJournal of the Neurological Sciences
Publication statusPublished - 2014

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