A case of discordant HbA1c: A method-dependent error

Goce Dimeski; Carel J. Pretorius; Anthony W. Russell; Stephen P. Miller; Robert J. Bird; Jacobus P.J. Ungerer

doi:10.5694/j.1326-5377.2009.tb02821.x

A case of discordant HbA_1c: A method-dependent error

Goce Dimeski, Carel J. Pretorius, Anthony W. Russell, Stephen P. Miller, Robert J. Bird, Jacobus P.J. Ungerer

Research output: Contribution to journal › Article › Research › peer-review

3 Citations (Scopus)

Abstract

Although glycated haemoglobin (HbA_1c) has become the key biochemical marker of long-term glycaemic control, analytical method-dependent differences in results can occur when haemoglobin variants are present or HbA_1c is reduced by decreased red cell survival. When the measured HbA_1c level is discordant with the patient's blood glucose measurements and clinical status, fructosamine is an alternative biochemical marker that can provide a more accurate estimate of the glycaemic control and enable clinicians to appropriately manage patients.

Original language	English
Pages (from-to)	347-349
Number of pages	3
Journal	The Medical Journal of Australia
Volume	191
Issue number	6
DOIs	https://doi.org/10.5694/j.1326-5377.2009.tb02821.x
Publication status	Published - 21 Sept 2009
Externally published	Yes

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10.5694/j.1326-5377.2009.tb02821.x

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AU - Bird, Robert J.

AU - Ungerer, Jacobus P.J.

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AB - Although glycated haemoglobin (HbA1c) has become the key biochemical marker of long-term glycaemic control, analytical method-dependent differences in results can occur when haemoglobin variants are present or HbA1c is reduced by decreased red cell survival. When the measured HbA1c level is discordant with the patient's blood glucose measurements and clinical status, fructosamine is an alternative biochemical marker that can provide a more accurate estimate of the glycaemic control and enable clinicians to appropriately manage patients.

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A case of discordant HbA1c: A method-dependent error

Abstract

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A case of discordant HbA_1c: A method-dependent error