A capacity for mixing in capillary wells for microplates

Jonathan Lye, Tuck Ng, Adrian Neild, Oi Wah Liew

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21 Citations (Scopus)


Sample/reagent mixing is important in microplate instrumentation and the approach of mixing prior to dispensation into the wells can be problematic when assays involve a mixture of different proportions of reagents. We demonstrate here with capillaries, a simple and highly effective method that uses air actuation and liquid surface tension to create pendant drops in which the inherent inner circulatory flow within accomplishes mixing. The approach portends the capability to be incorporated into microplates in order to provide a useful feature for assay investigations.
Original languageEnglish
Pages (from-to)152 - 154
Number of pages3
JournalAnalytical Biochemistry
Issue number1
Publication statusPublished - 2011

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