A brief history of COMBINE

Chris J. Myers, Gary Bader, Padraig Gleeson, Martin Golebiewski, Michael Hucka, Nicolas Le Novere, David P. Nickerson, Falk Schreiber, Dagmar Waltemath

Research output: Chapter in Book/Report/Conference proceedingConference PaperOther

1 Citation (Scopus)


Standards for data exchange are critical to the development of any field. They enable researchers and practitioners to transport information reliably, to apply a variety of tools to their problems, and to reproduce scientific results. Over the past two decades, a range of standards have been developed to facilitate the exchange and reuse of information in the domain of representation and modeling of biological systems. These standards are complementary, so the interactions between their developers increased over time. By the end of the last decade, the community of researchers decided that more interoperability is required between the standards, and that common development is needed to make better use of effort, time, and money devoted to this activity. The COmputational MOdeling in Biology NEtwork (COMBINE) was created to enable the sharing of resources, tools, and other infrastructure. This paper provides a brief history of this endeavor and the challenges that remain.

Original languageEnglish
Title of host publication2017 Winter Simulation Conference
EditorsVictor Chan, Andrea D’Ambrogio, Gregory Zacharewicz, Navonil Mustafee
Place of PublicationPiscataway NJ USA
PublisherIEEE, Institute of Electrical and Electronics Engineers
Number of pages12
ISBN (Electronic)9781538634288, 9781538634295
ISBN (Print)9781538634301
Publication statusPublished - 2017
Externally publishedYes
EventWinter Simulation Conference 2017 - Las Vegas, United States of America
Duration: 3 Dec 20176 Dec 2017


ConferenceWinter Simulation Conference 2017
Abbreviated titleWSC 2017
Country/TerritoryUnited States of America
CityLas Vegas
Internet address

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