TY - JOUR
T1 - A 24-months Follow-up Study of Individuals with Endometriosis using Transvaginal Ultrasound
AU - Gwata, Nyasha
AU - Hui, Ally
AU - Wong, Lufee
AU - Thee, Li Jing
AU - Tsaltas, Jim
AU - Mol, Ben
N1 - Publisher Copyright:
© 2024 AAGL
PY - 2024/8
Y1 - 2024/8
N2 - Study Objective: To investigate the progression of deep infiltrating endometriosis using transvaginal ultrasound surveillance of patients undergoing conservative management. Design: Retrospective single cohort. Setting: Australian tertiary university hospital Patients: One hundred twenty two women with endometriosis proven on transvaginal ultrasound who had not undergone surgical management. Interventions: The progression of endometriosis lesions demonstrated on transvaginal ultrasound in women receiving conservative management over the course of 24 months. Measurements and Main Results: A total of 122 patients fulfilled the inclusion criteria. All women had 2 ultrasounds that were performed at least 6 months apart. The median follow-up time was 490.5 days (255.4–725.6). At second scan, 22% (95% CI: 15–30%) of cohort experienced an increase in the number of endometriosis nodules compared to first scan, with 51% (95% CI: 42–60%) remaining static while 27% (95% CI: 19–35%) experienced a decrease. While there was no statistically significant difference in the volumes of uterosacral ligament, retro cervical, and bowel endometriosis, endometrioma volumes were significantly lower at second scan (Median = 3.24 mL, IQR = 0.6–16.87) as compared to the first scan (Median = 7.41 mL, IQR = 2.04–28.95), p <.001. Conclusion: Individuals with deep infiltrating endometriosis are unlikely to see significant disease progression over time. Both surgical and nonsurgical interventions are effective in managing endometriosis in terms of endometriotic nodule size and number, as measured by ultrasound.
AB - Study Objective: To investigate the progression of deep infiltrating endometriosis using transvaginal ultrasound surveillance of patients undergoing conservative management. Design: Retrospective single cohort. Setting: Australian tertiary university hospital Patients: One hundred twenty two women with endometriosis proven on transvaginal ultrasound who had not undergone surgical management. Interventions: The progression of endometriosis lesions demonstrated on transvaginal ultrasound in women receiving conservative management over the course of 24 months. Measurements and Main Results: A total of 122 patients fulfilled the inclusion criteria. All women had 2 ultrasounds that were performed at least 6 months apart. The median follow-up time was 490.5 days (255.4–725.6). At second scan, 22% (95% CI: 15–30%) of cohort experienced an increase in the number of endometriosis nodules compared to first scan, with 51% (95% CI: 42–60%) remaining static while 27% (95% CI: 19–35%) experienced a decrease. While there was no statistically significant difference in the volumes of uterosacral ligament, retro cervical, and bowel endometriosis, endometrioma volumes were significantly lower at second scan (Median = 3.24 mL, IQR = 0.6–16.87) as compared to the first scan (Median = 7.41 mL, IQR = 2.04–28.95), p <.001. Conclusion: Individuals with deep infiltrating endometriosis are unlikely to see significant disease progression over time. Both surgical and nonsurgical interventions are effective in managing endometriosis in terms of endometriotic nodule size and number, as measured by ultrasound.
KW - Deep infiltrating
KW - Endometriosis
KW - Progression
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=85192179182&partnerID=8YFLogxK
U2 - 10.1016/j.jmig.2024.04.010
DO - 10.1016/j.jmig.2024.04.010
M3 - Article
C2 - 38692482
AN - SCOPUS:85192179182
SN - 1553-4650
VL - 31
SP - 695
EP - 703
JO - Journal of Minimally Invasive Gynecology
JF - Journal of Minimally Invasive Gynecology
IS - 8
ER -