8-Chloro-5-(4-phenethylpiperazin-1 - Yl)pyrido[2,3-b][1,5]benzoxazepine

Benny Capuano, Ian Travers Crosby, Craig Macdonald Forsyth, Edward John Lloyd, Amelia Vom, Elizabeth Yuriev

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)


As part of an antipsychotic drug discovery program, we report the crystal structure of the title compound, C24H23ClN4O. The molecule has a tricyclic framework with a characteristic buckled V-shaped pyridobenzoxazepine unit, with the central seven-membered heterocycle in a boat configuration. The piperazine ring displays a chair conformation with the 2-phenyl-ethyl substituent assuming an equatorial orientation. There are two crystallographically independent, but virtually identical, molecules in the asymmetric unit.
Original languageEnglish
Pages (from-to)O1865 - O1866
Number of pages1
JournalActa Crystallographica Section E: Structure Reports Online
Issue numberPart 10
Publication statusPublished - 2008

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