8-Chloro-5-(4-phenethylpiperazin-1 - Yl)pyrido[2,3-b][1,5]benzoxazepine

Benny Capuano; Ian Travers Crosby; Craig Macdonald Forsyth; Edward John Lloyd; Amelia Vom; Elizabeth Yuriev

8-Chloro-5-(4-phenethylpiperazin-1 - Yl)pyrido[2,3-b][1,5]benzoxazepine

Benny Capuano, Ian Travers Crosby, Craig Macdonald Forsyth, Edward John Lloyd, Amelia Vom, Elizabeth Yuriev

Research output: Contribution to journal › Article › Research › peer-review

Abstract

As part of an antipsychotic drug discovery program, we report the crystal structure of the title compound, C24H23ClN4O. The molecule has a tricyclic framework with a characteristic buckled V-shaped pyridobenzoxazepine unit, with the central seven-membered heterocycle in a boat configuration. The piperazine ring displays a chair conformation with the 2-phenyl-ethyl substituent assuming an equatorial orientation. There are two crystallographically independent, but virtually identical, molecules in the asymmetric unit.

Original language	English
Pages (from-to)	O1865 - O1866
Number of pages	1
Journal	Acta Crystallographica Section E: Structure Reports Online
Volume	64
Issue number	Part 10
Publication status	Published - 2008

Cite this

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title = "8-Chloro-5-(4-phenethylpiperazin-1 - Yl)pyrido[2,3-b][1,5]benzoxazepine",

abstract = "As part of an antipsychotic drug discovery program, we report the crystal structure of the title compound, C24H23ClN4O. The molecule has a tricyclic framework with a characteristic buckled V-shaped pyridobenzoxazepine unit, with the central seven-membered heterocycle in a boat configuration. The piperazine ring displays a chair conformation with the 2-phenyl-ethyl substituent assuming an equatorial orientation. There are two crystallographically independent, but virtually identical, molecules in the asymmetric unit.",

author = "Benny Capuano and Crosby, {Ian Travers} and Forsyth, {Craig Macdonald} and Lloyd, {Edward John} and Amelia Vom and Elizabeth Yuriev",

year = "2008",

language = "English",

volume = "64",

pages = "O1865 -- O1866",

journal = "Acta Crystallographica Section E: Structure Reports Online",

issn = "1600-5368",

publisher = "International Union of Crystallography (IUCr)",

number = "Part 10",

}

TY - JOUR

T1 - 8-Chloro-5-(4-phenethylpiperazin-1 - Yl)pyrido[2,3-b][1,5]benzoxazepine

AU - Capuano, Benny

AU - Crosby, Ian Travers

AU - Forsyth, Craig Macdonald

AU - Lloyd, Edward John

AU - Vom, Amelia

AU - Yuriev, Elizabeth

PY - 2008

Y1 - 2008

N2 - As part of an antipsychotic drug discovery program, we report the crystal structure of the title compound, C24H23ClN4O. The molecule has a tricyclic framework with a characteristic buckled V-shaped pyridobenzoxazepine unit, with the central seven-membered heterocycle in a boat configuration. The piperazine ring displays a chair conformation with the 2-phenyl-ethyl substituent assuming an equatorial orientation. There are two crystallographically independent, but virtually identical, molecules in the asymmetric unit.

AB - As part of an antipsychotic drug discovery program, we report the crystal structure of the title compound, C24H23ClN4O. The molecule has a tricyclic framework with a characteristic buckled V-shaped pyridobenzoxazepine unit, with the central seven-membered heterocycle in a boat configuration. The piperazine ring displays a chair conformation with the 2-phenyl-ethyl substituent assuming an equatorial orientation. There are two crystallographically independent, but virtually identical, molecules in the asymmetric unit.

M3 - Article

SN - 1600-5368

VL - 64

SP - O1865 - O1866

JO - Acta Crystallographica Section E: Structure Reports Online

JF - Acta Crystallographica Section E: Structure Reports Online

IS - Part 10

ER -