8-Chloro-11-[4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazino]-5H- dibenzo[b,e][1,4]diazepine

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Abstract

A method to synthesize desmethylclozapine, 3, is reported. The procedure afforded the target compound in 69% yield. A by-product, isolated from the reaction mixture in 11% yield, proved to be the title compound, 4.

Original languageEnglish
Pages (from-to)329-332
Number of pages4
JournalMolecules
Volume4
Issue number11
DOIs
Publication statusPublished - 1999

Keywords

  • Amidine formation
  • Desmethylclozapine
  • Titanium tetrachloride

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