46, XX DSD comprise the most common group of genital abnormalities, with congenital adrenal hyperplasia (CAH) being the most important, not only because of its frequency but also because of its life-threatening complications without treatment. The different disorders are described, showing the range of genetic and enzymatic anomalies that lead to excess androgen production causing abnormal virilisation of a female foetus. The non-hormonal anatomical defects of genital development are also mentioned.
|Title of host publication||Disorders of Sex Development: An Integrated Approach to Management|
|Number of pages||9|
|Publication status||Published - 1 Jan 2012|