46, xx Disorders of Sex Development

Garry L. Warne, Jacqueline K. Hewitt

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46, XX DSD comprise the most common group of genital abnormalities, with congenital adrenal hyperplasia (CAH) being the most important, not only because of its frequency but also because of its life-threatening complications without treatment. The different disorders are described, showing the range of genetic and enzymatic anomalies that lead to excess androgen production causing abnormal virilisation of a female foetus. The non-hormonal anatomical defects of genital development are also mentioned.

Original languageEnglish
Title of host publicationDisorders of Sex Development: An Integrated Approach to Management
Number of pages9
ISBN (Electronic)9783642229640
ISBN (Print)9783642229633
Publication statusPublished - 1 Jan 2012
Externally publishedYes

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