4-Amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5h)-one, an isoguanosine analog

Ronald J. Quinn; Peter J. Scammells

doi:10.1071/CH9911001

4-Amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5h)-one, an isoguanosine analog

Ronald J. Quinn, Peter J. Scammells

Medicinal Chemistry

Research output: Contribution to journal › Article › Research › peer-review

4 Citations (Scopus)

Abstract

5-Amino-1-phenylpyrazole-4-carboxamide was condensed with benzoyl isothiocyanate. The resulting thiourea was treated with dicyclohexylcarbodiimide and annulated with ethanolic ammonia to yield 4-amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5H)-one. This product is a 1-phenylpyrazolo[3, 4-d] pyrimidine analogue of the biologically active natural product, isoguanosine. © 1991 ASEG.

Original language	English
Pages (from-to)	1001-1005
Number of pages	5
Journal	Australian Journal of Chemistry
Volume	44
Issue number	7
DOIs	https://doi.org/10.1071/CH9911001
Publication status	Published - 1 Jan 1991

Access to Document

10.1071/CH9911001

Cite this

@article{b604aa098c5949bd8b39d0d1aa4d041b,

title = "4-Amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5h)-one, an isoguanosine analog",

abstract = "5-Amino-1-phenylpyrazole-4-carboxamide was condensed with benzoyl isothiocyanate. The resulting thiourea was treated with dicyclohexylcarbodiimide and annulated with ethanolic ammonia to yield 4-amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5H)-one. This product is a 1-phenylpyrazolo[3, 4-d] pyrimidine analogue of the biologically active natural product, isoguanosine. {\textcopyright} 1991 ASEG.",

author = "Quinn, {Ronald J.} and Scammells, {Peter J.}",

year = "1991",

month = jan,

day = "1",

doi = "10.1071/CH9911001",

language = "English",

volume = "44",

pages = "1001--1005",

journal = "Australian Journal of Chemistry",

issn = "0004-9425",

publisher = "CSIRO Publishing",

number = "7",

}

TY - JOUR

T1 - 4-Amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5h)-one, an isoguanosine analog

AU - Quinn, Ronald J.

AU - Scammells, Peter J.

PY - 1991/1/1

Y1 - 1991/1/1

N2 - 5-Amino-1-phenylpyrazole-4-carboxamide was condensed with benzoyl isothiocyanate. The resulting thiourea was treated with dicyclohexylcarbodiimide and annulated with ethanolic ammonia to yield 4-amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5H)-one. This product is a 1-phenylpyrazolo[3, 4-d] pyrimidine analogue of the biologically active natural product, isoguanosine. © 1991 ASEG.

AB - 5-Amino-1-phenylpyrazole-4-carboxamide was condensed with benzoyl isothiocyanate. The resulting thiourea was treated with dicyclohexylcarbodiimide and annulated with ethanolic ammonia to yield 4-amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5H)-one. This product is a 1-phenylpyrazolo[3, 4-d] pyrimidine analogue of the biologically active natural product, isoguanosine. © 1991 ASEG.

UR - http://www.scopus.com/inward/record.url?scp=84970602582&partnerID=8YFLogxK

U2 - 10.1071/CH9911001

DO - 10.1071/CH9911001

M3 - Article

AN - SCOPUS:84970602582

SN - 0004-9425

VL - 44

SP - 1001

EP - 1005

JO - Australian Journal of Chemistry

JF - Australian Journal of Chemistry

IS - 7

ER -

4-Amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5h)-one, an isoguanosine analog

Abstract

Access to Document

Other files and links

Cite this