4-Amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5h)-one, an isoguanosine analog

Ronald J. Quinn, Peter J. Scammells

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5-Amino-1-phenylpyrazole-4-carboxamide was condensed with benzoyl isothiocyanate. The resulting thiourea was treated with dicyclohexylcarbodiimide and annulated with ethanolic ammonia to yield 4-amino-1-phenylpyrazolo[3, 4-d]pyrimidin-6(5H)-one. This product is a 1-phenylpyrazolo[3, 4-d] pyrimidine analogue of the biologically active natural product, isoguanosine. © 1991 ASEG.
Original languageEnglish
Pages (from-to)1001-1005
Number of pages5
JournalAustralian Journal of Chemistry
Issue number7
Publication statusPublished - 1 Jan 1991

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