Abstract
Mild traumatic brain injury (MTBI) or concussive injury affects 1.7 million Americans annually, of which 300,000 are due to recreational activities and contact sports, such as football, rugby, and boxing[1]. Finding the neuroanatomical correlates of brain TBI non-invasively and precisely is crucial for diagnosis and prognosis. Several studies have shown the in influence of traumatic brain injury (TBI) on the integrity of brain WM [2-4]. The vast majority of these works focus on athletes with diagnosed concussions. However, in contact sports, athletes are subjected to repeated hits to the head throughout the season, and we hypothesize that these have an influence on white matter integrity. In particular, the corpus callosum (CC), as a small structure connecting the brain hemispheres, may be particularly affected by torques generated by collisions, even in the absence of full blown concussions. Here, we use a combined surface-based morphometry and relative pose analyses, applying on the point distribution model (PDM) of the CC, to investigate TBI related brain structural changes between 9 pre-season and 9 post-season contact sport athlete MRIs. All the data are fed into surface based morphometry analysis and relative pose analysis. The former looks at surface area and thickness changes between the two groups, while the latter consists of detecting the relative translation, rotation and scale between them.
Original language | English |
---|---|
Title of host publication | Medical Imaging 2014 |
Subtitle of host publication | Image Processing |
Editors | Sebastien Ourselin, Martin A. Styner |
Place of Publication | USA |
Publisher | SPIE - International Society for Optical Engineering |
Number of pages | 6 |
Volume | 9034 |
ISBN (Print) | 9780819498274 |
DOIs | |
Publication status | Published - 1 Jan 2014 |
Externally published | Yes |
Event | Medical Imaging 2014: Image Processing - San Diego, United States of America Duration: 16 Feb 2014 → 18 Feb 2014 http://spie.org/Publications/Proceedings/Volume/9034 |
Conference
Conference | Medical Imaging 2014: Image Processing |
---|---|
Country | United States of America |
City | San Diego |
Period | 16/02/14 → 18/02/14 |
Internet address |