3D pre-versus post-season comparisons of surface and relative pose of the corpus callosum in contact sport athletes

Yi Lao, Niharika Gajawelli, Lauren Haas, Bryce Wilkins, Darryl Hwang, Sinchai Tsao, Yalin Wang, Meng Law, Natasha Leporé

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

1 Citation (Scopus)


Mild traumatic brain injury (MTBI) or concussive injury affects 1.7 million Americans annually, of which 300,000 are due to recreational activities and contact sports, such as football, rugby, and boxing[1]. Finding the neuroanatomical correlates of brain TBI non-invasively and precisely is crucial for diagnosis and prognosis. Several studies have shown the in influence of traumatic brain injury (TBI) on the integrity of brain WM [2-4]. The vast majority of these works focus on athletes with diagnosed concussions. However, in contact sports, athletes are subjected to repeated hits to the head throughout the season, and we hypothesize that these have an influence on white matter integrity. In particular, the corpus callosum (CC), as a small structure connecting the brain hemispheres, may be particularly affected by torques generated by collisions, even in the absence of full blown concussions. Here, we use a combined surface-based morphometry and relative pose analyses, applying on the point distribution model (PDM) of the CC, to investigate TBI related brain structural changes between 9 pre-season and 9 post-season contact sport athlete MRIs. All the data are fed into surface based morphometry analysis and relative pose analysis. The former looks at surface area and thickness changes between the two groups, while the latter consists of detecting the relative translation, rotation and scale between them.

Original languageEnglish
Title of host publicationMedical Imaging 2014
Subtitle of host publicationImage Processing
EditorsSebastien Ourselin, Martin A. Styner
Place of PublicationUSA
Number of pages6
ISBN (Print)9780819498274
Publication statusPublished - 1 Jan 2014
Externally publishedYes
EventConference on Medical Imaging - Image Processing 2014 - San Diego, United States of America
Duration: 16 Feb 201418 Feb 2014
http://spie.org/Publications/Proceedings/Volume/9034 (Proceedings)


ConferenceConference on Medical Imaging - Image Processing 2014
Country/TerritoryUnited States of America
CitySan Diego
Internet address

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