3-{5-Ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazol-2- yl}benzoic acid

Yeong Keng Yoon, Mohamed Ashraf Ali, Soo Choon Tan, Mohd Mustaqim Rosli, Ibrahim Abdul Razak

Research output: Contribution to journalArticleResearchpeer-review

Abstract

In the title compound, C24H25N3O5, the ethoxy group is disordered over two orientations in a 0.853 (14):0.147 (14) ratio. The benzimadazole ring system (r.m.s. deviation = 0.016 Å) makes a dihedral angle of 35.47 (7)° with the attached benzene ring. The pyrrolidine ring adopts an envelope conformation with a methylene C atom as the flap. In the crystal, inversion dimers linked by pairs of O - H⋯N hydrogen bonds generate R 2 2(16) loops. C - H⋯O interactions link the dimers into a three-dimensional network.

Original languageEnglish
Pages (from-to)o304
JournalActa Crystallographica Section E: Structure Reports Online
Volume69
Issue number2
DOIs
Publication statusPublished - Feb 2013
Externally publishedYes

Keywords

  • data-to-parameter ratio = 19.0
  • disorder in main residue
  • mean σ(C-C) = 0.003 Å
  • R factor = 0.064
  • single-crystal X-ray study
  • T = 100 K
  • wR factor = 0.134

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