The thienobenzodiazepine nucleus of the title compound, olanzapine methanol solvate monohydrate, C17H20N4S·CH 4O·H2O, is buckled, with the central seven-membered heterocycle in a boat conformation and the dihedral angle between the planes of the aromatic rings being 118°. The piperazine ring displays an almost perfect chair conformation with the methyl group assuming an equatorial orientation. The relative position of the thienobenzodiazepine and piperazine ring system is controlled by the planarity of the piperazine N in the amidine moiety.
|Number of pages||3|
|Journal||Acta Crystallographica Section E: Structure Reports Online|
|Publication status||Published - 1 Sep 2003|