1,6-Bis(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy)hexane

Jonathan B. Baell; Robert W. Gable; Andrew J. Harvey

doi:10.1107/S1600536804011067

1,6-Bis(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy)hexane

Jonathan B. Baell, Robert W. Gable, Andrew J. Harvey

Research output: Contribution to journal › Article › Research › peer-review

5 Citations (Scopus)

Abstract

The khellinone dimer, 1,6-bis-(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy) hexane, C₃₀H₃₄O₁₀, was prepared as part of a series of Kv1.3 ion channel blockers. The dimer lies on a centre of symmetry, and adopts an extended structure such that the separation between the benzofuran groups is 9.927 (3) Å. C-H⋯O hydrogen bonds link the molecules into linear chains which lie parallel to the [201] direction.

Original language	English
Journal	Acta Crystallographica Section E: Structure Reports Online
Volume	60
Issue number	6
DOIs	https://doi.org/10.1107/S1600536804011067
Publication status	Published - 1 Jun 2004
Externally published	Yes

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title = "1,6-Bis(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy)hexane",

abstract = "The khellinone dimer, 1,6-bis-(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy) hexane, C30H34O10, was prepared as part of a series of Kv1.3 ion channel blockers. The dimer lies on a centre of symmetry, and adopts an extended structure such that the separation between the benzofuran groups is 9.927 (3) {\AA}. C-H⋯O hydrogen bonds link the molecules into linear chains which lie parallel to the [201] direction.",

author = "Baell, \{Jonathan B.\} and Gable, \{Robert W.\} and Harvey, \{Andrew J.\}",

year = "2004",

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T1 - 1,6-Bis(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy)hexane

AU - Baell, Jonathan B.

AU - Gable, Robert W.

AU - Harvey, Andrew J.

PY - 2004/6/1

Y1 - 2004/6/1

N2 - The khellinone dimer, 1,6-bis-(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy) hexane, C30H34O10, was prepared as part of a series of Kv1.3 ion channel blockers. The dimer lies on a centre of symmetry, and adopts an extended structure such that the separation between the benzofuran groups is 9.927 (3) Å. C-H⋯O hydrogen bonds link the molecules into linear chains which lie parallel to the [201] direction.

AB - The khellinone dimer, 1,6-bis-(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy) hexane, C30H34O10, was prepared as part of a series of Kv1.3 ion channel blockers. The dimer lies on a centre of symmetry, and adopts an extended structure such that the separation between the benzofuran groups is 9.927 (3) Å. C-H⋯O hydrogen bonds link the molecules into linear chains which lie parallel to the [201] direction.

UR - https://www.scopus.com/pages/publications/18444368735

U2 - 10.1107/S1600536804011067

DO - 10.1107/S1600536804011067

M3 - Article

AN - SCOPUS:18444368735

SN - 1600-5368

VL - 60

JO - Acta Crystallographica Section E: Structure Reports Online

JF - Acta Crystallographica Section E: Structure Reports Online

IS - 6

ER -

1,6-Bis(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy)hexane

Abstract

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