Understanding the structural basis for Family B G protein-coupled receptor function

Sexton, Patrick (Primary Chief Investigator (PCI))
Furness, Sebastian (Chief Investigator (CI))
Kobilka, Brian (Chief Investigator (CI))
Wootten, Denise (Chief Investigator (CI))

Drug Discovery Biology

Project: Research

24 Article
2 Review Article

2 results

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2017

Allostery and Biased Agonism at Class B G Protein-Coupled Receptors
Wootten, D., Miller, L. J., Koole, C., Christopoulos, A. & Sexton, P. M., 11 Jan 2017, In: Chemical Reviews. 117, 1, p. 111-138 28 p.
Research output: Contribution to journal › Review Article › Research › peer-review

90 Citations (Scopus)
2016

Glucagon-like peptide-1 and its class B G protein-coupled receptors: a long march to therapeutic successes
de Graaf, C., Donnelly, D., Wootten, D., Lau, J., Sexton, P. M., Miller, L. J., Ahn, J-M., Liao, J., Fletcher, M. M., Yang, D., Brown, A. J. H., Zhou, C., Deng, J. & Wang, M-W., 1 Oct 2016, In: Pharmacological Reviews. 68, 4, p. 954-1013 60 p.
Research output: Contribution to journal › Review Article › Research › peer-review

267 Citations (Scopus)