Understanding novel drug binding pockets at G protein-coupled receptors

Valant, Celine (Primary Chief Investigator (PCI))

Drug Discovery Biology

Project: Research

Status	Finished
Effective start/end date	1/01/15 → 31/12/17

Funding

National Health & Medical Research Council (NHMRC): AUD412,077.00
National Health & Medical Research Council (NHMRC)

Related content

Research Output

Structure-based discovery of selective positive allosteric modulators of antagonists for the M₂ muscarinic acetylcholine receptor

Research output: Contribution to journal › Article › Research › peer-review

Accelerated structure-based design of chemically diverse allosteric modulators of a muscarinic G protein-coupled receptor

Research output: Contribution to journal › Article › Research › peer-review

Utility of an "allosteric site-impaired" M₂ muscarinic acetylcholine receptor as a novel construct for validating mechanisms of action of synthetic and putative endogenous allosteric modulators

Research output: Contribution to journal › Article › Research › peer-review