Transforming the treatment landscape in elderly Acute Myeloid Leukaemia (AML)

Wei, Andrew (Primary Chief Investigator (PCI))
Bohlander, Stefan K. (Chief Investigator (CI))
Reynolds, John (Chief Investigator (CI))
Levis, Mark (Chief Investigator (CI))

Epidemiology and Preventive Medicine Alfred Hospital

Project: Research

Status	Finished
Effective start/end date	1/05/19 → 31/12/22

4 Article

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia
Moujalled, D. M., Brown, F. C., Chua, C. C., Dengler, M. A., Pomilio, G., Anstee, N. S., Litalien, V., Thompson, E., Morley, T., MacRaild, S., Tiong, I. S., Morris, R., Dun, K., Zordan, A., Shah, J., Banquet, S., Halilovic, E., Morris, E., Herold, M. J., Lessene, G., & 5 othersAdams, J. M., Huang, D. C. S., Roberts, A. W., Blombery, P. & Wei, A. H., 9 Feb 2023, In: Blood. 141, 6, p. 634–644 11 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

11 Citations (Scopus)
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias
Thijssen, R., Diepstraten, S. T., Moujalled, D., Chew, E., Flensburg, C., Shi, M. X., Dengler, M. A., Litalien, V., MacRaild, S., Chen, M., Anstee, N. S., Reljić, B., Gabriel, S. S., Djajawi, T. M., Riffkin, C. D., Aubrey, B. J., Chang, C., Tai, L., Xu, Z., Morley, T., & 16 othersPomilio, G., Bruedigam, C., Kallies, A., Stroud, D. A., Bajel, A., Kluck, R. M., Lane, S. W., Schoumacher, M., Banquet, S., Majewski, I. J., Strasser, A., Roberts, A. W., Huang, D. C. S., Brown, F. C., Kelly, G. L. & Wei, A. H., 20 May 2021, In: Blood. 137, 20, p. 2721-2735 15 p.
Research output: Contribution to journal › Article › Research › peer-review

56 Citations (Scopus)
Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined With Modified Intensive Chemotherapy
Chua, C. C., Roberts, A. W., Reynolds, J., Fong, C. Y., Ting, S. B., Salmon, J. M., MacRaild, S., Ivey, A., Tiong, I. S., Fleming, S., Brown, F. C., Loo, S., Majewski, I. J., Bohlander, S. K. & Wei, A. H., 20 Oct 2020, In: Journal of Clinical Oncology. 38, 30, p. 3506-3517 12 p.
Research output: Contribution to journal › Article › Research › peer-review

93 Citations (Scopus)

FlowCore
Andrew Fryga (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility

Transforming the treatment landscape in elderly Acute Myeloid Leukaemia (AML)

Project Details

Research output

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined With Modified Intensive Chemotherapy

Equipment

FlowCore