Towards Clinical Translation of a Cell-based Therapy for Pelvic Organ Prolapse

Research output

Research output per year 2015 2019 2020 2022

• 18 Article
• 3 Review Article

Research output per year

Research output per year

Search results

• 2022

  Vaginal pressure sensor measurement during maximal voluntary pelvic floor contraction correlates with vaginal birth and pelvic organ prolapse—A pilot study

  Parkinson, L. A., Karjalainen, P. K., Mukherjee, S., Papageorgiou, A. W., Kulkarni, M., Arkwright, J. W., Young, N., Werkmeister, J. A., Davies-Tuck, M., Gargett, C. E. & Rosamilia, A., Feb 2022, In: Neurourology and Urodynamics. 41, 2, p. 592-600 9 p.

  Research output: Contribution to journal › Article › Research › peer-review
  3 Citations (Scopus)
• 2020

  A novel tropoelastin-based resorbable surgical mesh for pelvic organ prolapse repair

  Aghaei-Ghareh-Bolagh, B., Mukherjee, S., Lockley, K. M., Mithieux, S. M., Wang, Z., Emmerson, S., Darzi, S., Gargett, C. E. & Weiss, A. S., Sept 2020, In: Materials Today Bio. 8, 11 p., 100081.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  10 Citations (Scopus)

• Comparing the effect of tgf-β receptor inhibition on human perivascular mesenchymal stromal cells derived from endometrium, bone marrow and adipose tissues

  Gurung, S., Ulrich, D., Sturm, M., Rosamilia, A., Werkmeister, J. A. & Gargett, C. E., 1 Dec 2020, In: Journal of Personalized Medicine. 10, 4, 19 p., 261.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  7 Citations (Scopus)

• Electrospun Nanofiber Meshes With Endometrial MSCs Modulate Foreign Body Response by Increased Angiogenesis, Matrix Synthesis, and Anti-Inflammatory Gene Expression in Mice: Implication in Pelvic Floor

  Mukherjee, S., Darzi, S., Paul, K., Cousins, F. L., Werkmeister, J. A. & Gargett, C. E., 24 Mar 2020, In: Frontiers in Pharmacology. 11, 18 p., 353.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  24 Citations (Scopus)

• Impact of Sustained Transforming Growth Factor-β Receptor Inhibition on Chromatin Accessibility and Gene Expression in Cultured Human Endometrial MSC

  Lucciola, R., Vrljicak, P., Gurung, S., Filby, C., Darzi, S., Muter, J., Ott, S., Brosens, J. J. & Gargett, C. E., 1 Sept 2020, In: Frontiers in Cell and Developmental Biology. 8, 15 p., 567610.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  13 Citations (Scopus)
• 2019

  3D bioprinted endometrial stem cells on melt electrospun poly ε-caprolactone mesh for pelvic floor application promote anti-inflammatory responses in mice

  Paul, K., Darzi, S., McPhee, G., Del Borgo, M. P., Werkmeister, J. A., Gargett, C. E. & Mukherjee, S., 1 Oct 2019, In: Acta Biomaterialia. 97, p. 162-176 15 p.

  Research output: Contribution to journal › Article › Research › peer-review
  71 Citations (Scopus)

• A fiber-optic sensor-based device for the measurement of vaginal integrity in women

  Parkinson, L. A., Rosamilia, A., Mukherjee, S., Papageorgiou, A. W., Melendez-Munoz, J., Werkmeister, J. A., Gargett, C. E. & Arkwright, J. W., 1 Nov 2019, In: Neurourology and Urodynamics. 38, 8, p. 2264-2272 9 p.

  Research output: Contribution to journal › Article › Research › peer-review
  3 Citations (Scopus)

• Blended Nanostructured Degradable Mesh with Endometrial Mesenchymal Stem Cells Promotes Tissue Integration and Anti-Inflammatory Response in Vivo for Pelvic Floor Application

  Mukherjee, S., Darzi, S., Rosamilia, A., Kadam, V. & Truong, Y., 1 Jan 2019, In: Biomacromolecules. 20, 1, p. 454-468 15 p.

  Research output: Contribution to journal › Article › Research › peer-review
  36 Citations (Scopus)

• Composite mesh design for delivery of autologous mesenchymal stem cells influences mesh integration, exposure and biocompatibility in an ovine model of pelvic organ prolapse

  Emmerson, S., Mukherjee, S., Melendez-Munoz, J., Cousins, F., Edwards, S. L., Karjalainen, P., Ng, M., Tan, K. S., Darzi, S., Bhakoo, K., Rosamilia, A., Werkmeister, J. A. & Gargett, C. E., 1 Dec 2019, In: Biomaterials. 225, 14 p., 119495.

  Research output: Contribution to journal › Article › Research › peer-review
  32 Citations (Scopus)

• Endometrial mesenchymal stem/stromal cell modulation of T cell proliferation

  Yang, X., Devianti, M., Yang, Y. H., Ong, Y. R., Tan, K. S., Gurung, S., Tan, J. L., Zhu, D., Lim, R., Gargett, C. E. & Deane, J. A., 1 Jan 2019, In: Reproduction. 157, 1, p. 43-52 10 p.

  Research output: Contribution to journal › Article › Research › peer-review
  12 Citations (Scopus)

• Mesenchymal stem cell-based bioengineered constructs: Foreign body response, cross-talk with macrophages and impact of biomaterial design strategies for pelvic floor disorders

  Mukherjee, S., Darzi, S., Paul, K., Werkmeister, J. A. & Gargett, C. E., 6 Aug 2019, In: Interface Focus. 9, 4, 15 p., 20180089.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access

  File
  45 Citations (Scopus)

• Tissue engineering approaches for treating pelvic organ prolapse using a novel source of stem/stromal cells and new materials

  Gargett, C., Gurung, S., Darzi, S., Werkmeister, J. & Mukherjee, S., 1 Jul 2019, In: Current Opinion in Urology. 29, 4, p. 450-457 8 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  27 Citations (Scopus)
• 2018

  Endometrial Mesenchymal Stem/Stromal Cells Modulate the Macrophage Response to Implanted Polyamide/Gelatin Composite Mesh in Immunocompromised and Immunocompetent Mice

  Darzi, S., Deane, J. A., Nold, C. A., Edwards, S. E., Gough, D. J., Mukherjee, S., Gurung, S., Tan, K. S., Vashi, A. V., Werkmeister, J. A. & Gargett, C. E., 1 Dec 2018, In: Scientific Reports. 8, 1, 15 p., 6554.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  29 Citations (Scopus)

• In Vivo Survival of Human Endometrial Mesenchymal Stem Cells Transplanted under the Kidney Capsule of Immunocompromised Mice

  Gurung, S., Deane, J. A., Darzi, S., Werkmeister, J. A. & Gargett, C. E., 1 Jan 2018, In: Stem Cells and Development. 27, 1, p. 35-43 9 p.

  Research output: Contribution to journal › Article › Research › peer-review
  29 Citations (Scopus)

• The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies

  Gurung, S., Williams, S., Deane, J. A., Werkmeister, J. A. & Gargett, C. E., 4 Dec 2018, In: Frontiers in Cell and Developmental Biology. 6, DEC, 15 p., 164.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  29 Citations (Scopus)
• 2017

  Ovine multiparity is associated with diminished vaginal muscularis, increased elastic fibres and vaginal wall weakness: Implication for pelvic organ prolapse

  Emmerson, S., Young, N., Rosamilia, A., Parkinson, L., Edwards, S. L., Vashi, A. V., Davies-Tuck, M., White, J., Elgass, K., Lo, C., Arkwright, J., Werkmeister, J. A. & Gargett, C. E., 4 Apr 2017, In: Scientific Reports. 7, 45709.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  23 Citations (Scopus)

• Vaginal wall weakness in parous ewes: a potential preclinical model of pelvic organ prolapse

  Young, N., Rosamilia, A., Arkwright, J., Lee, J., Davies-Tuck, M., Melendez, J., Werkmeister, J. & Gargett, C. E., Jul 2017, In: International Urogynecology Journal. 28, 7, p. 999 - 1004 6 p.

  Research output: Contribution to journal › Article › Research › peer-review
  18 Citations (Scopus)
• 2016

  Endometrial stem/progenitor cells: the first 10 years

  Gargett, C. E., Schwab, K. E. & Deane, J. A., Mar 2016, In: Human Reproduction Update. 22, 2, p. 137-163 27 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  385 Citations (Scopus)

• Identification and characterization of human endometrial mesenchymal stem/stromal cells and their potential for cellular therapy

  Darzi, S., Werkmeister, J. A., Deane, J. A. & Gargett, C. E., Sept 2016, In: Stem Cells Translational Medicine. 5, 9, p. 1127-1132 6 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access

  File
  69 Citations (Scopus)

• Real-time measurement of the vaginal pressure profile using an optical-fiber-based instrumented speculum

  Parkinson, L. A., Gargett, C. E., Young, N., Rosamilia, A., Vashi, A. V., Werkmeister, J. A., Papageorgiou, A. W. & Arkwright, J. W., 1 Dec 2016, In: Journal of Biomedical Optics. 21, 12, 7 p., 127008.

  Research output: Contribution to journal › Article › Research › peer-review
  9 Citations (Scopus)
• 2015

  Stem cells in endometrial physiology

  Gurung, S., Deane, J. A., Masuda, H., Maruyama, T. & Gargett, C. E., 2015, In: Seminars in Reproductive Medicine. 33, 5, p. 326 - 332 7 p.

  Research output: Contribution to journal › Article › Research › peer-review
  30 Citations (Scopus)