Clostridium difficile is a major cause of disease in food production animals and humans and is the major cause of hospital-acquired diarrhoea worldwide. More virulent animal and human isolates have emerged since 2000, resulting in epidemics. C. difficile may also be transmitted from food to humans, however, little is known about how C. difficile causes disease in animals. This project will analyse the virulence properties of animal isolates of C. difficile and will make a significant contribution to our understanding of how these strains cause disease. Rational preventative and treatment regimes can then be designed to prevent C. difficile outbreaks in Australia.
|Effective start/end date||4/01/10 → 31/12/12|
- Australian Research Council (ARC): AUD330,000.00
- University of Western Australia