The role of Moz, an epigenetic regulator, in the pathogenesis of leukaemia

Baell, Jonathan (Primary Chief Investigator (PCI))
Thomas, Tim (Chief Investigator (CI))
Voss, Anne (Chief Investigator (CI))

Medicinal Chemistry

Project: Research

Status	Finished
Effective start/end date	1/01/12 → 31/12/14

Funding

National Health and Medical Research Council (NHMRC) (Australia): A$118,564.00

2 Article
1 Letter

Discovery of Potent and Fast-Acting Antimalarial Bis-1,2,4-triazines
Priebbenow, D. L., Mathiew, M., Shi, D. H., Harjani, J. R., Beveridge, J. G., Chavchich, M., Edstein, M. D., Duffy, S., Avery, V. M., Jacobs, R. T., Brand, S., Shackleford, D. M., Wang, W., Zhong, L., Lee, G., Tay, E., Barker, H., Crighton, E., White, K. L. & Charman, S. A. & 3 others, De Paoli, A., Creek, D. J. & Baell, J. B., 8 Apr 2021, In: Journal of Medicinal Chemistry. 64, 7, p. 4150-4162 13 p.
Research output: Contribution to journal › Article › Research › peer-review

15 Citations (Scopus)
Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents
Priebbenow, D. L., Leaver, D. J., Nguyen, N., Cleary, B., Lagiakos, H. R., Sanchez, J., Xue, L., Huang, F., Sun, Y., Mujumdar, P., Mudududdla, R., Varghese, S., Teguh, S., Charman, S. A., White, K. L., Shackleford, D. M., Katneni, K., Cuellar, M., Strasser, J. M. & Dahlin, J. L. & 13 others, Walters, M. A., Street, I. P., Monahan, B. J., Jarman, K. E., Jousset Sabroux, H., Falk, H., Chung, M. C., Hermans, S. J., Downer, N. L., Parker, M. W., Voss, A. K., Thomas, T. & Baell, J. B., 14 May 2020, In: Journal of Medicinal Chemistry. 63, 9, p. 4655-4684 30 p.
Research output: Contribution to journal › Article › Research › peer-review

16 Citations (Scopus)
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth
Baell, J. B., Leaver, D. J., Hermans, S. J., Kelly, G. L., Brennan, M. S., Downer, N. L., Nguyen, N., Wichmann, J., McRae, H. M., Yang, Y., Cleary, B., Lagiakos, H. R., Mieruszynski, S., Pacini, G., Vanyai, H. K., Bergamasco, M. I., May, R. E., Davey, B. K., Morgan, K. J. & Sealey, A. J. & 32 others, Wang, B., Zamudio, N., Wilcox, S., Garnham, A. L., Sheikh, B. N., Aubrey, B. J., Doggett, K., Chung, M. C., de Silva, M., Bentley, J., Pilling, P., Hattarki, M., Dolezal, O., Dennis, M. L., Falk, H., Ren, B., Charman, S. A., White, K. L., Rautela, J., Newbold, A., Hawkins, E. D., Johnstone, R. W., Huntington, N. D., Peat, T. S., Heath, J. K., Strasser, A., Parker, M. W., Smyth, G. K., Street, I. P., Monahan, B. J., Voss, A. K. & Thomas, T., 9 Aug 2018, In: Nature. 560, 7717, p. 253-257 5 p.
Research output: Contribution to journal › Letter › Research › peer-review

Open Access
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207 Citations (Scopus)

The role of Moz, an epigenetic regulator, in the pathogenesis of leukaemia

Project Details

Funding

Research output

Discovery of Potent and Fast-Acting Antimalarial Bis-1,2,4-triazines

Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth