The role of cross-reactive T cells in severe lung disease following viral respiratory infections

Purcell, Anthony (Primary Chief Investigator (PCI))
Kotsimbos, Tom (Chief Investigator (CI))
Mifsud, Nicole (Chief Investigator (CI))

Project: Research

Status	Finished
Effective start/end date	1/01/15 → 31/12/18

Funding

National Health and Medical Research Council (NHMRC) (Australia): A$965,569.25

11 Article
3 Review Article

HLA-A^∗11:01-restricted CD8⁺ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people
Habel, J. R., Nguyen, A. T., Rowntree, L. C., Szeto, C., Mifsud, N. A., Clemens, E. B., Loh, L., Chen, W., Rockman, S., Nelson, J., Davies, J., Miller, A., Tong, S. Y. C., Rossjohn, J., Gras, S., Purcell, A. W., Hensen, L., Kedzierska, K. & Illing, P. T., Mar 2022, In: PLoS Pathogens. 18, 3, 28 p., e1010337.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

20 Citations (Scopus)
T Cell Epitope Discovery in the Context of Distinct and Unique Indigenous HLA Profiles
Hensen, L., Illing, P. T., Rowntree, L. C., Davies, J., Miller, A., Tong, S. Y. C., Habel, J. R., van de Sandt, C. E., Flanagan, K., Purcell, A. W., Kedzierska, K. & Clemens, E. B., 6 May 2022, In: Frontiers in Immunology. 13, 23 p., 812393.
Research output: Contribution to journal › Review Article › Research › peer-review

Open Access

11 Citations (Scopus)
CD8⁺ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
Hensen, L., Illing, P. T., Bridie Clemens, E., Nguyen, T. H. O., Koutsakos, M., van de Sandt, C. E., Mifsud, N. A., Nguyen, A. T., Szeto, C., Chua, B. Y., Halim, H., Rizzetto, S., Luciani, F., Loh, L., Grant, E. J., Saunders, P. M., Brooks, A. G., Rockman, S., Kotsimbos, T. C. & Cheng, A. C. & 16 others, Richards, M., Westall, G. P., Wakim, L. M., Loudovaris, T., Mannering, S. I., Elliott, M., Tangye, S. G., Jackson, D. C., Flanagan, K. L., Rossjohn, J., Gras, S., Davies, J., Miller, A., Tong, S. Y. C., Purcell, A. W. & Kedzierska, K., 18 May 2021, In: Nature Communications. 12, 1, 20 p., 2931.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

28 Citations (Scopus)

Australian Synchrotron
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility

The role of cross-reactive T cells in severe lung disease following viral respiratory infections

Project Details

Funding

Research output

HLA-A∗11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people

T Cell Epitope Discovery in the Context of Distinct and Unique Indigenous HLA Profiles

CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

Equipment

Australian Synchrotron

HLA-A^∗11:01-restricted CD8⁺ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people

CD8⁺ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph