The role of cross-reactive T cells in severe lung disease following viral respiratory infections

Purcell, Anthony (Primary Chief Investigator (PCI))
Kotsimbos, Tom (Chief Investigator (CI))
Mifsud, Nicole (Chief Investigator (CI))

Project: Research

Status	Finished
Effective start/end date	1/01/15 → 31/12/18

Funding

National Health and Medical Research Council (NHMRC) (Australia): A$965,569.25

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10 Article
2 Review Article

CD8⁺ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
Hensen, L., Illing, P. T., Bridie Clemens, E., Nguyen, T. H. O., Koutsakos, M., van de Sandt, C. E., Mifsud, N. A., Nguyen, A. T., Szeto, C., Chua, B. Y., Halim, H., Rizzetto, S., Luciani, F., Loh, L., Grant, E. J., Saunders, P. M., Brooks, A. G., Rockman, S., Kotsimbos, T. C., Cheng, A. C. & 16 others, Richards, M., Westall, G. P., Wakim, L. M., Loudovaris, T., Mannering, S. I., Elliott, M., Tangye, S. G., Jackson, D. C., Flanagan, K. L., Rossjohn, J., Gras, S., Davies, J., Miller, A., Tong, S. Y. C., Purcell, A. W. & Kedzierska, K., 18 May 2021, In: Nature Communications. 12, 1, 20 p., 2931.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

3 Citations (Scopus)
A comprehensive review and performance evaluation of bioinformatics tools for HLA class I peptide-binding prediction
Mei, S., Li, F., Leier, A., Marquez-Lago, T. T., Giam, K., Croft, N. P., Akutsu, T., Smith, A. I., Li, J., Rossjohn, J., Purcell, A. W. & Song, J., Jul 2020, In: Briefings in Bioinformatics. 21, 4, p. 1119-1135 17 p., bbz051.
Research output: Contribution to journal › Review Article › Research › peer-review

43 Citations (Scopus)
A shared TCR bias toward an immunogenic EBV epitope dominates in HLA-B*07: 02-Expressing individuals
Rowntree, L. C., Nguyen, T. H. O., Farenc, C., Halim, H., Hensen, L., Rossjohn, J., Kotsimbos, T. C., Purcell, A. W., Kedzierska, K., Gras, S. & Mifsud, N. A., 15 Sep 2020, In: Journal of Immunology. 205, 6, p. 1524-1534 11 p.
Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Australian Synchrotron
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility

The role of cross-reactive T cells in severe lung disease following viral respiratory infections

Project Details

Funding

Research output

CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

A comprehensive review and performance evaluation of bioinformatics tools for HLA class I peptide-binding prediction

A shared TCR bias toward an immunogenic EBV epitope dominates in HLA-B*07: 02-Expressing individuals

Equipment

Australian Synchrotron

CD8⁺ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph