The role of Clostridium difficile virulence factors in mediating the host-pathogen interactions that lead to gastrointestinal disease

Lyras, Dena (Primary Chief Investigator (PCI))
Carter, Glen, (Chief Investigator (CI))
Rood, Julian (Chief Investigator (CI))

Microbiology

Project: Research

Status	Finished
Effective start/end date	1/01/13 → 31/12/15

Funding

National Health & Medical Research Council (NHMRC): AUD429,014.13

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Research Output

Utility of the clostridial site-specific recombinase TnpX to clone toxic-product-encoding genes and selectively remove genomic DNA fragments

Research output: Contribution to journal › Article › Research › peer-review

Clostridium difficile virulence factors: insights into an anaerobic spore-forming pathogen

Research output: Contribution to journal › Article › Research › peer-review

CdtR regulates TcdA and TcdB production in Clostridium difficile

Research output: Contribution to journal › Article › Research › peer-review

Defining the roles of TcdA and TcdB in localized gastrointestinal disease, systemic organ damage, and the host response during clostridium difficile Infections

Research output: Contribution to journal › Article › Research › peer-review

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

Research output: Contribution to journal › Article › Other › peer-review

Small animal models for the study of Clostridium difficile disease pathogenesis

Research output: Contribution to journal › Article › Research › peer-review

Regulation of toxin production in the pathogenic clostridia

Research output: Contribution to journal › Article › Research › peer-review