The regulation and evolution of posttranscriptional gene networks

The ability of cells to regulate gene expression is key for organism development, adaptation to new environments, and evolutionary changes that shape the diversity of life on Earth. This project studies the RNA binding proteins called PUFs which are central for gene expression in diverse organisms. I will use cutting-edge new generation Systems Biology approaches to study how PUF proteins regulate genes to enable metabolic adaptation, differentiation of cell types, and the evolution of new gene expression outputs in distinct biological species. The outcomes will be new insight and fundamental knowledge of the regulation and evolution of posttranscriptional gene networks.