The molecular basis by which the interleukin-6 cytokine promotes emphysema

Jenkins, Brendan (Primary Chief Investigator (PCI))
Anderson, Gary P. (Chief Investigator (CI))
Rose-John, Stefan (Chief Investigator (CI))

Hudson Institute - Centre for Innate Immunity and Infectious Disease

Project: Research

Status	Finished
Effective start/end date	1/01/15 → 31/12/17

Funding

National Health and Medical Research Council (NHMRC) (Australia): A$638,813.00

2 Article

IL6 trans-signaling promotes KRAS-driven lung carcinogenesis
Brooks, G. D., McLeod, L., Alhayyani, S., Miller, A., Russell, P. A., Ferlin, W., Rose-John, S., Ruwanpura, S. & Jenkins, B. J., 15 Feb 2016, In: Cancer Research. 76, 4, p. 866-876 11 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

95 Citations (Scopus)
Therapeutic targeting of the IL-6 trans-signaling/mechanistic target of rapamycin complex 1 axis in pulmonary emphysema
Ruwanpura, S. M., McLeod, L., Dousha, L. F., Seow, H. J., Alhayyani, S., Tate, M. D., Deswaerte, V., Brooks, G. D., Bozinovski, S., MacDonald, M., Garbers, C., King, P. T., Bardin, P. G., Vlahos, R., Rose-John, S., Anderson, G. P. & Jenkins, B. J., 15 Dec 2016, In: American Journal of Respiratory and Critical Care Medicine. 194, 12, p. 1494-1505 12 p.
Research output: Contribution to journal › Article › Research › peer-review

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41 Citations (Scopus)