The host specificity of bacterial pathogens

  • Hartland, Elizabeth (Primary Chief Investigator (PCI))
  • Robins-Browne, Roy (Chief Investigator (CI))
  • Frankel, Gad M (Partner Investigator (PI))

Project: Research

Project Details

Project Description

The vast majority of microorganisms that cause diseases in animals are host specific. In other words, they cause disease exclusively in a particular animal species, but are harmless for others. Despite considerable recent advances in our understanding of the mechanisms used by microorganisms in general to cause disease, in most cases the underlying basis of host-specificity is not known. In this project, we will use two animal pathogens, rabbit-specific enteropathogenic E. coli and the closely related bacterium, Citrobacter rodentium, which specifically infect rabbits and mice respectively, to investigate the molecular basis of host specificity.
StatusFinished
Effective start/end date1/01/0431/12/06

Funding

  • Australian Research Council (ARC): AUD225,000.00
  • Monash University