The biogenesis of bacterial outer membranes: how bacteria build their surface coating.

  • Lithgow, Trevor (Primary Chief Investigator (PCI))
  • Clements, Abigail (Chief Investigator (CI))

Project: Research

Project Details

Project Description

Biological membranes envelope the cells of all organisms and growth and division of cells requires constant
addition of new protein and lipid constituents to the membranes. We will determine the mechanism by which
protein and lipid molecules are inserted into the outer membrane of bacterial cells. Exciting new
technological advances now make this a feasible undertaking. Completion of the project will provide
understanding of how the bacterial outer membrane is built from its component parts, and what can be done
to manipulate the process. Expected outcomes are detailed knowledge of the mechanism of membrane
assembly, and how this process is regulated in bacteria.
Effective start/end date1/01/1131/12/13


  • Australian Research Council (ARC): AUD84,462.00
  • Australian Research Council (ARC): AUD245,538.00
  • Monash University
  • Australian Research Council (ARC)