A pragmatic, single-blind, cluster randomised controlled trial will be conducted nationally in GP clinics (n=40). Community dwelling adults with a history of moderate-severe COPD will be identified within each clinic (n = 10) by trained practice nurses. Control clinic subjects (n=200) will receive a booklet on ‘lung health’. The intervention includes a multidimensional assessment by a practice nurse to characterise TTs in patients with COPD that will lead to a personalised medicine approach targeting pulmonary, extrapulmonary and behavioural traits. In the intervention group (n=200), trained practice nurses will coordinate: a personalised COPD action plan, home-based pulmonary rehabilitation, home medicines review, smoking cessation support, and tailored mobile phone-based risk reduction support. Changes in HRQoL at 6 months is the primary efficacy end point. Respiratory acute hospital visits per participant at 6 and 12 months will be assessed.
|Short title||Targeting treatable traits in copd|
|Effective start/end date||15/12/20 → 1/06/25|
- Treatable Traits
- health-related quality of life