Targeting the Plasmodium falciparum Metalloaminopeptidases for Development of New Antimalarial Agents

Project: Research

Status	Finished
Effective start/end date	1/01/14 → 31/12/16

Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases
Vinh, N. B., Drinkwater, N., Malcolm, T. R., Kassiou, M., Lucantoni, L., Grin, P. M., Butler, G. S., Duffy, S., Overall, C. M., Avery, V. M., Scammells, P. J. & McGowan, S., 24 Jan 2019, In: Journal of Medicinal Chemistry. 62, 2, p. 622-640 19 p.
Research output: Contribution to journal › Article › Research › peer-review

26 Citations (Scopus)
Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions
Lee, J., Vinh, N. B., Drinkwater, N., Yang, W., Kannan Sivaraman, K., Schembri, L. S., Gazdik, M., Grin, P. M., Butler, G. S., Overall, C. M., Charman, S. A., McGowan, S. & Scammells, P. J., 8 Aug 2019, In: Journal of Medicinal Chemistry. 62, 15, p. 7185-7209 25 p.
Research output: Contribution to journal › Article › Research › peer-review

17 Citations (Scopus)
Mapping the Pathway and Dynamics of Bestatin Inhibition of the Plasmodium falciparum M1 Aminopeptidase PfA-M1
Yang, W., Riley, B. T., Lei, X., Porebski, B. T., Kass, I., Buckle, A. M. & McGowan, S., 6 Dec 2018, In: ChemMedChem. 13, 23, p. 2504-2513 10 p.
Research output: Contribution to journal › Article › Research › peer-review

10 Citations (Scopus)

Project Details