Targeting pyroptosis to limit the severity of influenza virus infections

Tate, Michelle (Primary Chief Investigator (PCI))
Lawlor, Kathryn (Associate Investigator (AI))
Mansell, Ashley (Associate Investigator (AI))
Hertzog, Paul (Associate Investigator (AI))

Project: Research

Status	Active
Effective start/end date	1/01/23 → 31/12/26

4 Article

Gasdermin E deficiency limits inflammation and lung damage during influenza virus infection
Rosli, S., Ambrose, R. L., Harpur, C. M., Lam, M., Hodges, C., Barry, K. T., West, A. C., Mansell, A., Lawlor, K. E. & Tate, M. D., 6 Jun 2025, In: Cell Death and Disease. 16, 1, 13 p., 440.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

10 Link opens in a new tab Citations (Scopus)
Aggregated Hendra virus C-protein activates the NLRP3 inflammasome to induce inflammation
Barry, K., Harpur, C., Lam, M., Tate, M. D. & Mansell, A., 10 Nov 2023, In: Journal of Inflammation. 20, 1, 12 p., 38.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

6 Link opens in a new tab Citations (Scopus)
A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases
Docherty, C. A. H., Fernando, A. J., Rosli, S., Lam, M., Dolle, R. E., Navia, M. A., Farquhar, R., La France, D., Tate, M. D., Murphy, C. K., Rossi, A. G. & Mansell, A., 22 Jun 2023, In: Clinical & Translational Immunology. 12, 6, 18 p., e1455.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

40 Link opens in a new tab Citations (Scopus)

3 Finished

Finding the balance – Reducing inflammation during severe influenza infections
Tate, M. (Primary Chief Investigator (PCI)) & Mansell, A. (Chief Investigator (CI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/20 → 31/12/22
Project: Research
Understanding and modulating hyperinflammation caused by influenza viruses
Tate, M. (Primary Chief Investigator (PCI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/17 → 30/09/21
Project: Research
The role of the inflammasome in modulating disease during influenza virus infection
Tate, M. (Primary Chief Investigator (PCI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/15 → 31/12/18
Project: Research

FlowCore (FLOW)
Fryga, A. (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Monash Animal Research Platform (MARP)
Findlay, C. (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Monash Histology Platform (MHP)
Cohen, C. (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility