Targeting pyroptosis to limit the severity of influenza virus infections

Project: Research

Status	Active
Effective start/end date	1/01/23 → 31/12/26

Gasdermin E deficiency limits inflammation and lung damage during influenza virus infection
Rosli, S., Ambrose, R. L., Harpur, C. M., Lam, M., Hodges, C., Barry, K. T., West, A. C., Mansell, A., Lawlor, K. E. & Tate, M. D., 6 Jun 2025, In: Cell Death & Disease. 16, 1, 13 p., 440.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
Aggregated Hendra virus C-protein activates the NLRP3 inflammasome to induce inflammation
Barry, K., Harpur, C., Lam, M., Tate, M. D. & Mansell, A., 10 Nov 2023, In: Journal of Inflammation. 20, 1, 12 p., 38.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

3 Citations (Scopus)
A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases
Docherty, C. A. H., Fernando, A. J., Rosli, S., Lam, M., Dolle, R. E., Navia, M. A., Farquhar, R., La France, D., Tate, M. D., Murphy, C. K., Rossi, A. G. & Mansell, A., 22 Jun 2023, In: Clinical & Translational Immunology. 12, 6, 18 p., e1455.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

26 Citations (Scopus)

Project Details