Targeting necroptosis in the race to treat acute and chronic inflammation

Research output

Research output per year 2023 2023 2023

• 3 Article

Research output per year

Research output per year

Search results

• 2023

  A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation

  Speir, M., Tye, H., Gottschalk, T. A., Simpson, D. S., Djajawi, T. M., Deo, P., Ambrose, R. L., Conos, S. A., Emery, J., Abraham, G., Pascoe, A., Hughes, S. A., Weir, A., Hawkins, E. D., Kong, I., Herold, M. J., Pearson, J. S., Lalaoui, N., Naderer, T. & Vince, J. E. & 1 others, Lawlor, K. E., 2023, In: EMBO Reports. 24, 11, 19 p., e56865.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  8   Link opens in a new tab Citations (Scopus)

• A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation

  Garnish, S. E., Martin, K. R., Kauppi, M., Jackson, V. E., Ambrose, R., Eng, V. V., Chiou, S., Meng, Y., Frank, D., Tovey Crutchfield, E. C., Patel, K. M., Jacobsen, A. V., Atkin-Smith, G. K., Di Rago, L., Doerflinger, M., Horne, C. R., Hall, C., Young, S. N., Cook, M. & Athanasopoulos, V. & 11 others, Vinuesa, C. G., Lawlor, K. E., Wicks, I. P., Ebert, G., Ng, A. P., Slade, C. A., Pearson, J. S., Samson, A. L., Silke, J., Murphy, J. M. & Hildebrand, J. M., 28 Sept 2023, In: Nature Communications. 14, 1, 17 p., 6046.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  13   Link opens in a new tab Citations (Scopus)

• The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase

  Pierotti, C. L., Jacobsen, A. V., Grohmann, C., Dempsey, R. K., Etemadi, N., Hildebrand, J. M., Fitzgibbon, C., Young, S. N., Davies, K. A., Kersten, W. J. A., Silke, J., Lowes, K. N., Sabroux, H. J., Huang, D. C. S., van Delft, M. F., Murphy, J. M. & Lessene, G., May 2023, In: Biochemical Journal. 480, 9, p. 665-684 20 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  14   Link opens in a new tab Citations (Scopus)