Targeting key regulators of innate immunity in inflammation-associated cancer

Jenkins, Brendan (Primary Chief Investigator (PCI))

Hudson Institute - Centre for Innate Immunity and Infectious Disease

Project: Research

Status	Relinquished
Effective start/end date	1/01/19 → 1/07/23

4 Article

Complete loss of miR-200 family induces EMT associated cellular senescence in gastric cancer
Yu, L., Cao, C., Li, X., Zhang, M., Gu, Q., Gao, H., Balic, J. J., Xu, D., Zhang, L., Ying, L., Xu, D., Yang, Y., Wu, D., He, B., Jenkins, B. J., Liu, Y. & Li, J., 3 Jan 2022, In: Oncogene. 41, 1, p. 26-36 11 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

17 Citations (Scopus)
Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma
Headland, S. E., Dengler, H. S., Xu, D., Teng, G., Everett, C., Ratsimandresy, R. A., Yan, D., Kang, J., Ganeshan, K., Nazarova, E. V., Gierke, S., Wedeles, C. J., Guidi, R., DePianto, D. J., Morshead, K. B., Huynh, A., Mills, J., Flanagan, S., Hambro, S., Nunez, V., & 24 othersKlementowicz, J. E., Shi, Y., Wang, J., Bevers, J., Ramirez-Carrozz, V., Pappu, R., Abbas, A., Heiden, J. V., Choy, D. F., Yadav, R., Modrusan, Z., Panettieri, R. A., Koziol-Whit, C., Jester, W. F., Jenkins, B. J., Cao, Y., Clarke, C., Austin, C., Lafkas, D., Xu, M., Wolters, P. J., Arron, J. R., West, N. R. & Wilson, M. S., 12 Jan 2022, In: Science Translational Medicine. 14, 627, 16 p., eabf8188.
Research output: Contribution to journal › Article › Research › peer-review

15 Citations (Scopus)
Toll-like Receptor 9 Promotes Initiation of Gastric Tumorigenesis by Augmenting Inflammation and Cellular Proliferation
Tang, K., McLeod, L., Livis, T., West, A. C., Dawson, R., Yu, L., Balic, J. J., Chonwerawong, M., Wray-McCann, G., Oshima, H., Oshima, M., Deswaerte, V., Ferrero, R. L. & Jenkins, B. J., Jan 2022, In: Cellular and Molecular Gastroenterology and Hepatology. 14, 3, p. 567-586 20 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

8 Citations (Scopus)

Animal Research Platform (MARP)
Christine Findlay (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
Histology Platform
Camilla Cohen (Manager)
Faculty of Medicine Nursing and Health Sciences Research Platforms
Facility/equipment: Facility
MHTP Medical Genomics Facility
Trevor Wilson (Manager)
Hudson Institute - Department of Molecular and Translational Science
Facility/equipment: Facility

Targeting key regulators of innate immunity in inflammation-associated cancer

Project Details

Research output

Complete loss of miR-200 family induces EMT associated cellular senescence in gastric cancer

Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma

Toll-like Receptor 9 Promotes Initiation of Gastric Tumorigenesis by Augmenting Inflammation and Cellular Proliferation

Equipment

Animal Research Platform (MARP)

Histology Platform

MHTP Medical Genomics Facility