Research output per year
Research output per year
- 26 results
Search results
-
2026
PDX-Atlas: A web-based portal to manage and share data from patient-derived xenograft models of cancer
Keerthikumar, S. (Leading Author), Clark, A. K., Wu, Y., Anderson, B., Da, Y., Qin, L., Choo, N., Porter, L. H., Kraska, J., Papargiris, M., Risbridger, G. P., Taylor, R. A., Lawrence, M. G. (Leading Author) & Goode, D. L. (Leading Author), 1 Nov 2026, In: Cancer Letters. 660, 5 p., 218836.Research output: Contribution to journal › Comment / Debate › Research › peer-review
Open Access -
2025
Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
Fidelito, G., Todorovski, I., Cluse, L., Vervoort, S. J., Taylor, R. A. & Watt, M. J., 22 Apr 2025, In: Cell Reports. 44, 4, 21 p., 115470.Research output: Contribution to journal › Article › Research › peer-review
Open Access13 Link opens in a new tab Citations (Scopus) -
p-AKT Protein Expression Predicts Response to AKT Inhibitor Combined with Docetaxel Therapy in Adenocarcinoma and Neuroendocrine Prostate Cancer
Werneck Gomes, H., Lister, N. L., Keerthikumar, S., Niranjan, B., Richards, M. G., Ryan, A., Kwan, E. M., Risbridger, G. P. & Taylor, R. A., 1 Jul 2025, In: Clinical Cancer Research. 31, 13, p. 2727-2740 14 p.Research output: Contribution to journal › Article › Research › peer-review
1 Link opens in a new tab Citation (Scopus) -
Reprogramming of Androgen Receptor Activity in Castration-resistant Prostate Cancer is Shaped by Truncated Variants
Lawrence, M. G. (Leading Author), Keerthikumar, S., Townley, S. L., Clark, A. K., Cuffe, G. B., Laven-Law, G., Hanson, A. R., Shrestha, R. K., Knutson, T. P., Richards, M. G., Teng, L., Choo, N., Crumbaker, M., Joshua, A. M., Corey, E., Nelson, P. S., Dehm, S. M., Risbridger, G. P., Tilley, W. D. & Hickey, T. E. & 2 others, , Sept 2025, In: European Urology Focus. 11, 5, p. 790-800 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Link opens in a new tab Citations (Scopus) -
Single-cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology
Quezada Urban, R. (Leading Author), Keerthikumar, S., Clark, A., Wang, H., Phipson, B., Bakshi, A., Ryan, A., Thorne, H., Taylor, R. A., Lawrence, M. G., Risbridger, G. P., Toivanen, R. & Goode, D. L. (Leading Author), Oct 2025, In: Molecular Oncology. 19, 10, p. 2776-2796 21 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
2024
Carboplatin in Metastatic Castrate Resistant Prostate Cancer: A Retrospective Study of Heavily Pretreated Patients (COMPACT)
Pemberton, L., Allen, C., Handel, E., Weickhardt, A., Shapiro, J., Tran, B., Taylor, R. A., Risbridger, G. P. & Pook, D. W., Apr 2024, In: Clinical Genitourinary Cancer. 22, 2, p. 580-585 6 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
Co-targeting BET, CBP, and p300 inhibits neuroendocrine signalling in androgen receptor-null prostate cancer
Choo, N. (Leading Author), Keerthikumar, S., Ramm, S., Ashikari, D., Teng, L., Niranjan, B., Hedwards, S., Porter, L. H., Goode, D. L., Simpson, K. J., Taylor, R. A., Risbridger, G. P. & Lawrence, M. G. (Leading Author), Jun 2024, In: Journal of Pathology. 263, 2, p. 242–256 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access14 Link opens in a new tab Citations (Scopus) -
Defining the challenges and opportunities for using patient-derived models in prostate cancer research
Brennen, W. N. (Leading Author), Le Magnen, C. (Leading Author), Karkampouna, S., Anselmino, N., Bock, N., Choo, N., Clark, A. K., Coleman, I. M., Dolgos, R., Ferguson, A. M., Goode, D. L., Krutihof-de Julio, M., Navone, N. M., Nelson, P. S., O'Neill, E., Porter, L. H., Ranasinghe, W., Sunada, T., Williams, E. D. & Butler, L. M. & 5 others, , 15 May 2024, In: The Prostate. 84, 7, p. 623-635 13 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access7 Link opens in a new tab Citations (Scopus) -
FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer
Wang, Z., Townley, S. L., Zhang, S., Liu, M., Li, M., Labaf, M., Patalano, S., Venkataramani, K., Siegfried, K. R., Macoska, J. A., Han, D., Gao, S., Risbridger, G. P., Taylor, R. A., Lawrence, M. G., He, H. H., Selth, L. A. & Cai, C., Dec 2024, In: Nature Communications. 15, 1, 20 p., 4914.Research output: Contribution to journal › Article › Research › peer-review
Open Access38 Link opens in a new tab Citations (Scopus) -
Left out in the cold: Moving beyond hormonal therapy for the treatment of immunologically cold prostate cancer with CAR T cell immunotherapies
Porter, L. H., Harrison, S. G., Risbridger, G. P., Lister, N. & Taylor, R. A., Oct 2024, In: The Journal of Steroid Biochemistry and Molecular Biology. 243, 12 p., 106571.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access8 Link opens in a new tab Citations (Scopus) -
Patient-derived castration-resistant prostate cancer model revealed CTBP2 upregulation mediated by OCT1 and androgen receptor
Obinata, D., Takayama, K., Lawrence, M. G., Funakoshi, D., Hara, M., Niranjan, B., Teng, L., Taylor, R. A., Risbridger, G. P., Takahashi, S. & Inoue, S., Dec 2024, In: BMC Cancer. 24, 1, 12 p., 554.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Link opens in a new tab Citations (Scopus) -
2023
Advances in preclinical models of prostate cancer for research discovery
Taylor, R. A., Lawrence, M. G. & Risbridger, G. P., 1 May 2023, In: Journal of Endocrinology. 257, 2, 10 p., e220245.Research output: Contribution to journal › Review Article › Research › peer-review
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Low-dose carboplatin modifies the tumor microenvironment to augment CAR T cell efficacy in human prostate cancer models
Porter, L. H., Zhu, J. J., Lister, N. L., Harrison, S. G., Keerthikumar, S., Goode, D. L., Urban, R. Q., Byrne, D. J., Azad, A., Vela, I., Hofman, M. S., Neeson, P. J., Darcy, P. K., Trapani, J. A., Taylor, R. A. & Risbridger, G. P., Dec 2023, In: Nature Communications. 14, 1, 17 p., 5346.Research output: Contribution to journal › Article › Research › peer-review
Open Access43 Link opens in a new tab Citations (Scopus) -
Multi-substrate Metabolic Tracing Reveals Marked Heterogeneity and Dependency on Fatty Acid Metabolism in Human Prostate Cancer
Fidelito, G., De Souza, D. P., Niranjan, B., De Nardo, W., Keerthikumar, S., Brown, K., Taylor, R. A. & Watt, M. J., 1 Apr 2023, In: Molecular cancer research : MCR. 21, 4, p. 359-373 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access14 Link opens in a new tab Citations (Scopus) -
2022
Hidden clues in prostate cancer – Lessons learned from clinical and pre-clinical approaches on diagnosis and risk stratification
Toivanen, R., Porter, L. H., Li, Z., Clouston, D., Risbridger, G. P. & Taylor, R. A., 1 Jan 2022, In: Cancer Letters. 524, p. 182-192 11 p.Research output: Contribution to journal › Article › Research › peer-review
5 Link opens in a new tab Citations (Scopus) -
Neuroendocrine cells in prostate cancer correlate with poor outcomes: a systematic review and meta-analysis
Kannan, A., Clouston, D., Frydenberg, M., Ilic, D., Karim, M. N., Evans, S. M., Toivanen, R., Risbridger, G. P. & Taylor, R. A., Oct 2022, In: BJU International. 130, 4, p. 420-433 14 p.Research output: Contribution to journal › Review Article › Research › peer-review
11 Link opens in a new tab Citations (Scopus) -
New approaches to targeting epigenetic regulation in prostate cancer
Thompson, D., Choo, N., Bolton, D. M., Lawrentschuk, N., Risbridger, G. P., Lawrence, M. G. & Taylor, R. A., Sept 2022, In: Current Opinion in Urology. 32, 5, p. 472-480 9 p.Research output: Contribution to journal › Review Article › Research › peer-review
7 Link opens in a new tab Citations (Scopus) -
Personalized Medicine for Prostate Cancer: Is Targeting Metabolism a Reality?
Fidelito, G., Watt, M. J. & Taylor, R. A., 21 Jan 2022, In: Frontiers in Oncology. 11, 15 p., 778761.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access26 Link opens in a new tab Citations (Scopus) -
Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer
Alizadeh-Ghodsi, M., Owen, K. L., Townley, S. L., Zanker, D., Rollin, S. P. G., Hanson, A. R., Shrestha, R., Toubia, J., Gargett, T., Chernukhin, I., Luu, J., Cowley, K. J., Clark, A., Carroll, J. S., Simpson, K. J., Winter, J. M., Lawrence, M. G., Butler, L. M., Risbridger, G. P. & Thierry, B. & 5 others, , Jul 2022, In: Cancer Research Communications. 2, 7, p. 706-724 19 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access18 Link opens in a new tab Citations (Scopus) -
2021
Androgen receptor enhancer amplification in matched patient-derived xenografts of primary and castrate-resistant prostate cancer
Porter, L. H., Bakshi, A., Pook, D., Clark, A., Clouston, D., Kourambas, J., MURAL investigators, Goode, D. L., Risbridger, G. P., Taylor, R. A. & Lawrence, M. G., Jun 2021, In: Journal of Pathology. 254, 2, p. 121-134 14 p.Research output: Contribution to journal › Article › Research › peer-review
25 Link opens in a new tab Citations (Scopus) -
High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids
Choo, N., Ramm, S., Luu, J., Winter, J. M., Selth, L. A., Dwyer, A. R., Frydenberg, M., Grummet, J., Sandhu, S., Hickey, T. E., Tilley, W. D., Taylor, R. A., Risbridger, G. P., Lawrence, M. G. & Simpson, K. J., Oct 2021, In: SLAS Discovery. 26, 9, p. 1107-1124 18 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access66 Link opens in a new tab Citations (Scopus) -
Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer
Fernandes, R. C., Toubia, J., Townley, S., Hanson, A. R., Dredge, B. K., Pillman, K. A., Bert, A. G., Winter, J. M., Iggo, R., Das, R., Obinata, D., MURAL investigators, Sandhu, S., Risbridger, G. P., Taylor, R. A., Lawrence, M. G., Butler, L. M., Zoubeidi, A., Gregory, P. A. & Tilley, W. D. & 3 others, , 5 Jan 2021, In: Cell Reports. 34, 1, 23 p., 108585.Research output: Contribution to journal › Article › Research › peer-review
Open Access47 Link opens in a new tab Citations (Scopus) -
The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology
Risbridger, G. P., Clark, A. K., Porter, L. H., Toivanen, R., Bakshi, A., Lister, N. L., Pook, D., Pezaro, C. J., Sandhu, S., Keerthikumar, S., Quezada Urban, R., Papargiris, M., Kraska, J., Madsen, H. B., Wang, H., Richards, M. G., Niranjan, B., O’Dea, S., Teng, L. & Wheelahan, W. & 25 others, , 19 Aug 2021, In: Nature Communications. 12, 1, 5049.Research output: Contribution to journal › Article › Research › peer-review
Open Access65 Link opens in a new tab Citations (Scopus) -
2020
Early intervention exercise training does not delay prostate cancer progression in Pten−/− mice
Taylor, R. A., Farrelly, S. G., Clark, A. K. & Watt, M. J., Aug 2020, In: The Prostate. 80, 11, p. 906-914 9 p.Research output: Contribution to journal › Article › Research › peer-review
4 Link opens in a new tab Citations (Scopus) -
Impact of human visceral and glutealfemoral adipose tissue transplant on glycemic control in a mouse model of diet-induced obesity
Tsiloulis, T., Raajendiran, A., Keenan, S. N., Ooi, G., Taylor, R. A., Burton, P. & Watt, M. J., Sept 2020, In: American Journal of Physiology - Endocrinology and Metabolism. 319, 3, p. E519-E528 10 p.Research output: Contribution to journal › Article › Research › peer-review
5 Link opens in a new tab Citations (Scopus) -
PDX: Moving beyond drug screening to versatile models for research discovery
Risbridger, G., Lawrence, M. & Taylor, R. A., 1 Nov 2020, In: Journal of the Endocrine Society. 4, 11, 9 p., bvaa132.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile28 Link opens in a new tab Citations (Scopus)