Targeting bacterial 'superbugs' by innovative combination dosing strategies and new antibiotics

Research Output

Characterizing the time-course of antihypertensive activity and optimal dose range of fimasartan via mechanism-based population modeling

Research output: Contribution to journal › Article › Research › peer-review

Combating Carbapenem-Resistant Acinetobacter baumannii by an Optimized Imipenem-plus-Tobramycin Dosage Regimen: Prospective Validation via Hollow-Fiber Infection and Mathematical Modeling

Research output: Contribution to journal › Article › Research › peer-review

Polymyxin resistance in Acinetobacter baumannii: genetic mutations and transcriptomic changes in response to clinically relevant dosage regimens

Research output: Contribution to journal › Article › Research › peer-review

Colistin and polymyxin B dosage regimens against Acinetobacter baumannii: differences in activity and the emergence of resistance

Research output: Contribution to journal › Article › Research › peer-review

Conjugation of 10 kDa linear PEG onto trastuzumab Fab′ is sufficient to significantly enhance lymphatic exposure while preserving in vitro biological activity

Research output: Contribution to journal › Article › Research › peer-review

Polymyxin B in combination with doripenem against heteroresistant Acinetobacter baumannii: pharmacodynamics of new dosing strategies

Research output: Contribution to journal › Article › Research › peer-review

Resistance suppression by high-intensity, short-duration aminoglycoside exposure against hypermutable and non-hypermutable Pseudomonas aeruginosa

Research output: Contribution to journal › Article › Research › peer-review

Compact, hydrophilic, lanthanide-binding tags for paramagnetic NMR spectroscopy

Research output: Contribution to journal › Article › Research › peer-review

Four Decades of β-Lactam Antibiotic Pharmacokinetics in Cystic Fibrosis

Research output: Contribution to journal › Article › Research › peer-review

Population pharmacokinetics and target attainment of meropenem in plasma and tissue of morbidly obese patients after laparoscopic intraperitoneal surgery

Research output: Contribution to journal › Article › Research › peer-review

Population pharmacokinetic modeling of the enterohepatic recirculation of fimasartan in rats, dogs, and humans

Research output: Contribution to journal › Article › Research › peer-review