Systems approaches to understanding mitochondrial function and dysfunction in disease

Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2

Wu, Y., Lim, Y-W., Stroud, D. A., Martel, N., Hall, T. E., Lo, H. P., Ferguson, C., Ryan, M. T., McMahon, K-A. & Parton, R. G., 13 Mar 2023, In: Developmental Cell. 58, 5, p. 376-397.e1-4 27 p.

Research output: Contribution to journal › Article › Research › peer-review

Multi-omics identifies large mitoribosomal subunit instability caused by pathogenic MRPL39 variants as a cause of pediatric onset mitochondrial disease

Amarasekera, S. S. C., Hock, D. H., Lake, N. J., Calvo, S. E., Grønborg, S. W., Krzesinski, E. I., Amor, D. J., Fahey, M. C., Simons, C., Wibrand, F., Mootha, V. K., Lek, M., Lunke, S., Stark, Z., Østergaard, E., Christodoulou, J., Thorburn, D. R., Stroud, D. A. & Compton, A. G., 20 Jul 2023, In: Human Molecular Genetics. 32, 15, p. 2441-2454 14 p.

Research output: Contribution to journal › Article › Research › peer-review

AIFM1 is a component of the mitochondrial disulfide relay that drives complex I assembly through efficient import of NDUFS5

Salscheider, S. L., Gerlich, S., Cabrera-Orefice, A., Peker, E., Rothemann, R. A., Murschall, L. M., Finger, Y., Szczepanowska, K., Ahmadi, Z. A., Guerrero-Castillo, S., Erdogan, A., Becker, M., Ali, M., Habich, M., Petrungaro, C., Burdina, N., Schwarz, G., Klußmann, M., Neundorf, I., Stroud, D. A., & 4 othersRyan, M. T., Trifunovic, A., Brandt, U. & Riemer, J., 1 Sept 2022, In: The EMBO Journal. 41, 17, 21 p., e110784.

Research output: Contribution to journal › Article › Research › peer-review