Structure-based design of novel therapeutics for multi-drug resistant Neisseria gonorrhoeae

Vrielink, Alice (Primary Chief Investigator (PCI))
Stubbs, Keith (Chief Investigator (CI))
Scanlon, Martin (Chief Investigator (CI))
Kahler, Charlene (Chief Investigator (CI))

Medicinal Chemistry

University of Western Australia

Project: Other

Acronym	LptA
Status	Finished
Effective start/end date	1/01/15 → 31/12/17

2 Article

Novel small molecules that increase the susceptibility of Neisseria gonorrhoeae to cationic antimicrobial peptides by inhibiting lipid A phosphoethanolamine transferase
Mullally, C., Stubbs, K. A., Thai, V. C., Anandan, A., Bartley, S., Scanlon, M. J., Jarvis, G. A., John, C. M., Lim, K. Y. L., Sullivan, C. M., Sarkar-Tyson, M., Vrielink, A. & Kahler, C. M., 25 Aug 2022, In: Journal of Antimicrobial Chemotherapy. 77, 9, p. 2441-2447 7 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)
Direct demonstration of lipid phosphorylation in the lipid bilayer of the biomimetic bicontinuous cubic phase using the confined enzyme lipid A phosphoethanolamine transferase
van 't Hag, L., Anandan, A., Seabrook, S. A., Gras, S. L., Drummond, C. J., Vrielink, A. & Conn, C. E., 21 Feb 2017, In: Soft Matter. 13, 7, p. 1493-1504 12 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

10 Citations (Scopus)

Monash Fragment Platform
Bradley Doak (Manager) & Martin Scanlon (Manager)
Faculty of Pharmacy and Pharmaceutical Sciences
Facility/equipment: Facility