Structure and mechanisms of RNA-targeting by CRISPR-Cas13a

Research output

Research output per year 2021 2021 2022 2022

• 4 Article

Research output per year

Research output per year

Search results

• 2022

  CRISPR–Cas9 bends and twists DNA to read its sequence

  Cofsky, J. C., Soczek, K. M., Knott, G. J., Nogales, E. & Doudna, J. A., Apr 2022, In: Nature Structural & Molecular Biology. 29, 4, p. 395-402 8 p.

  Research output: Contribution to journal › Article › Research › peer-review
  43 Citations (Scopus)

• Crystal structure of an RNA/DNA strand exchange junction

  Cofsky, J. C., Knott, G. J., Gee, C. L. & Doudna, J. A., Apr 2022, In: PLoS ONE. 17, 4, 15 p., e0263547.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  3 Citations (Scopus)
• 2021

  Accelerated RNA detection using tandem CRISPR nucleases

  Liu, T. Y., Knott, G. J., Smock, D. C. J., Desmarais, J. J., Son, S., Bhuiya, A., Jakhanwal, S., Prywes, N., Agrawal, S., Díaz de León Derby, M., Switz, N. A., Armstrong, M., Harris, A. R., Charles, E. J., Thornton, B. W., Fozouni, P., Shu, J., Stephens, S. I., Kumar, G. R. & Zhao, C. & 15 others, Mok, A., Iavarone, A. T., Escajeda, A. M., McIntosh, R., Kim, S., Dugan, E. J., IGI Testing Consortium, Pollard, K. S., Tan, M. X., Ott, M., Fletcher, D. A., Lareau, L. F., Hsu, P. D., Savage, D. F. & Doudna, J. A., Sept 2021, In: Nature Chemical Biology. 17, 9, p. 982-988 7 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  165 Citations (Scopus)

• Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy

  Fozouni, P., Son, S., Díaz de León Derby, M., Knott, G. J., Gray, C. N., D'Ambrosio, M. V., Zhao, C., Switz, N. A., Kumar, G. R., Stephens, S. I., Boehm, D., Tsou, C. L., Shu, J., Bhuiya, A., Armstrong, M., Harris, A. R., Chen, P. Y., Osterloh, J. M., Meyer-Franke, A. & Joehnk, B. & 12 others, Walcott, K., Sil, A., Langelier, C., Pollard, K. S., Crawford, E. D., Puschnik, A. S., Phelps, M., Kistler, A., DeRisi, J. L., Doudna, J. A., Fletcher, D. A. & Ott, M., 21 Jan 2021, In: Cell. 184, 2, p. 323-333.e9 20 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  677 Citations (Scopus)