Structural and functional alteration of red blood cells by Babesia parasites

  • Cooke, Brian, (Primary Chief Investigator (PCI))
  • Smith, Ian (Chief Investigator (CI))
  • McElwain, Terry (Partner Investigator (PI))
  • Narla, Mohandas (Partner Investigator (PI))

Project: Research

Project Description

The tick-borne parasite Babesia bovis causes significant disease in cattle in Australia and a sizeable economic loss. The parasites alter red blood cells causing severe, often fatal disease, but the mechanisms by which they do this are not understood. In this grant, we will identify novel parasite proteins involved in red blood cell modification and discover how they contribute to severe disease. Our results will underpin future development of new veterinary vaccines and drugs.
StatusFinished
Effective start/end date4/01/1031/12/12

Funding

  • Australian Research Council (ARC): AUD350,000.00
  • Monash University