Research output per year
Research output per year
Project Details
Project Description
The central aim of this project is to develop cutting-edge modelling frameworks by incorporating burst
process in gene expression into stochastic models in order to achieve deeper insights into the mechanisms
that regulate gene expression. Using two important genetic networks as the testable paradigm, realistic
models will be designed for the first time to examine the critical functions of burst process in generating cellto-
cell variations. Computer simulations will provide reconciliation between hypotheses and may lead to
discoveries regarding the regulatory mechanisms in gene expression. The novel and rigorous approaches
are capable to model a wide range of biological systems with burst process.
process in gene expression into stochastic models in order to achieve deeper insights into the mechanisms
that regulate gene expression. Using two important genetic networks as the testable paradigm, realistic
models will be designed for the first time to examine the critical functions of burst process in generating cellto-
cell variations. Computer simulations will provide reconciliation between hypotheses and may lead to
discoveries regarding the regulatory mechanisms in gene expression. The novel and rigorous approaches
are capable to model a wide range of biological systems with burst process.
| Status | Finished |
|---|---|
| Effective start/end date | 2/05/11 → 28/04/16 |
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Inference method for developing mathematical models of cell signaling pathways using proteomic datasets
Tian, T. & Song, J., 2017, Bioinformatics: Volume II: Structure, Function, and Applications. Keith, J. M. (ed.). 2 ed. New York NY USA: Humana Press, Vol. 1526. p. 329-344 16 p. (Methods in Molecular Biology; vol. 1526).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Research › peer-review
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A new cost-profit model for measuring the optimal scale of China’s foreign exchange reserve
Li, X. & Tian, T., 2016, In: Mathematical Problems in Engineering. 2016, p. 1-10 10 p., 9261297.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Stability analysis for second-order stochastic neutral partial functional systems subject to infinite delays and impulses
Jiang, F., Yang, H. & Tian, T., 1 Dec 2016, In: Advances in Difference Equations. 2016, 1, p. 1-11 11 p., 224.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Citations (Scopus)